Toll Free: 18008891064
  • Home
  • About Us
  • Product List
    • ONCOLOGY
      • Cytalux (Pofalacianine)
      • Pylarify (Piflufolastat F18)
      • Truseltiq (Infigratinib)
      • Enhertu (Trastuzumab Deruxtecan)
      • Mektovi (Binimetinib)
      • Braftovi (Encorafenib)
      • Libtayo (Cemiplimab-rwlc)
      • Lorbrena (Lorlatinib)
      • Talzenna (Talazoparib)
      • Balversa (Erdafitinib)
      • Piqray (Alpelisib)
      • Alunbrig (Brigatinib)
      • Jemperli (Dostarlimab-gxly)
      • Tepmetko (Tepotinib)
      • COSELA (Trilaciclib)
      • Fotivda (Tivozanib)
      • Rozlytrek (Entrectinib)
      • Tivdak® (tisotumab vedotin-tftv)
      • Ayvakit (Avapritinib)
      • Tazverik (Tazemetostat)
      • Tukysa (Tucatinib)
      • Pemazyre (Pemigatinib)
      • Trodelvy (Sacituzumab govitecan-hziy)
      • Tabrecta (Capmatinib)
      • Retevmo (Selpercatinib)
      • Zepzelca (Lurbinectedin)
      • Gavreto (Pralsetinib)
      • MARGENZATM (margetuximab-cmkb)
      • Orgovyx (relugolix)
      • DANYELZA (naxitamab-gqgk)
      • ZEJULA (Niraparib)
      • VERZENIO (Abemaciclib)
      • TECENTRIQ (Atezolizumab)
      • NERLYNX (Neratinib)
      • Yervoy
      • CAPRELSA (Vandetnib)
      • CELSENTRI (Maraviroc)
      • CIDOFOVIR (Visitide)
      • IBRANCE (Palbociclib Capsules)
      • COMETRIQ (Cabozantinib)
      • CYRAMZA (Ramucirumab Injection)
      • DABRAFENIB (Tafinlar)
      • ENTEREG (Almiopan Capsule)
      • ERIVEDGE (Vismodegib Tablet)
      • LYNPARZA (Olaparib)
      • Qinlock (Ripretinib)
      • MEKINIST (Trametnib Tablet)
      • Mitotane (Lysodren)
      • NAVELBINE ORAL (Vinorelbine)
      • TEYSUNO (Tegafur)
      • ZELBORAF (Vemurafenib Tablet)
      • Zepzelca (Lurbinectedin)
      • ZYDELIG (Idelalisib)
    • HEMATOLOGY
      • Rezurock (Belumosudil)
      • Empaveli (Pegcetacoplan)
      • Idhifa (Enasidenib)
      • Besponsa (Inotuzumab Ozogamicin)
      • Tibsovo (Ivosidenib)
      • Poteligeo (Mogamulizumab-kpkc)
      • Xospata (Gilteritinib)
      • Asparlas (Calaspargase pegol-mknl)
      • Polivy (Polatuzumab Vedotin-piiqa
      • Reblozyl (Luspatercept–aamt)
      • Ukoniq (Umbralisib)
      • Pepaxto (Melphalan Flufenamide)
      • Zynlonta (Loncastuximab Tesirine-lpyl)
      • Rylaze
      • Exkivity (Mobocertinib)
      • SCEMBLIX®(Asciminib)
      • Besremi (Ropeginterferon alfa-2b-njft)
      • SARCLISA® (isatuximab-irfc)
      • Inqovi (decitabine and cedazuridine)
      • Blenrep (Belantamab Mafodotin-blmf)
      • Monjuvi (Tafasitamab-cxix)
      • TAFINLAR (Dabrafenib)
      • CALQUENCE (Acalabrutinib)
      • MYLOTARG Gemtuzumab
      • Aliqopa(Copanlisib)
      • Brentuximab Vedotin
      • AGRYLIN (Anagrelide Hydrochloride)
      • ATRIANCE (Nelarabine)
      • BLINCYTO (Blinatumomab)
      • ONCASPAR (Pegaspargase)
      • ERWINAZE (Asparaginase Erwinia Chrysanthemi)
      • FOLOTYN (Pralatrexate)
      • TREOSULFAN (Treosulfan)
      • Ponatinib
      • NPLATE (Romiplostim)
      • KYPROLIS (Carfilzomib)
      • MABCAMPATH (Alemtuzumab)
      • VENCLEXTA (Venetoclax)
      • SOLIRIS (eculizumab)
      • SYNRIBO (Omacetaxine Mepesuccinate)
      • ALKERAN (Melphalan)
      • FARYDAK (Panobinostat)
      • BOSULIF (Bosutinib)
      • ELDISINE (Vindesine Sulphate)
      • Ixazomib Citrate
      • TEPADINA (Thiotepa)
      • ZOLINZA (Vorinostat)
    • Nephrology
      • Ultomiris (Ravulizumab)
    • GASTROENTROLOGY
      • VOSEVI (Sofosbuvir, Velpatasvir, And Voxilaprevir)
      • OLYSIO (SIMEPREVIR)
      • SYPRINE (Trientine HCL)
    • NEUROLOGY
      • Azstarys (Serdexmethylphenidate and Dexmethylphenidate)
      • Qelbree (Viloxazine)
      • Lybalvi (Olanzapine and Samidorphan)
      • Aduhelm (aducanumab-avwa)
      • NUEDEXTA (Dextromethorphan Hydrobromide)
      • ILARIS (Canakinumab)
      • GLIOLAN (Aminolevulinic acid hydrochloride)
      • STELARA (Ustekinumab)
      • HUMIRA (Adalimumab)
    • IMMUNOLOGY
      • Ocrevus (Ocrelizumab)
      • Skyrizi (Risankizumab-rzaa)
      • PONVORY®(ponesimod)
      • Zeposia (Ozanimod)
      • SILIQ (Brodalumab)
      • TREMFYA (Guselkumab)
    • RARE DISEASES
      • Nulibry (Fosdenopterin)
      • Welireg (Belzutifan)
      • Xiaflex (Collagenase Clostridium Histolyticum)
      • Mepsevii (Vestronidase alfa-vjbk)
      • Symdeko (Tezacaftor/Ivacaftor & Ivacaftor)
      • Palynziq (Pegvaliase-pqpz)
      • Onpattro (Patisiran)
      • Galafold (Migalastat)
      • Diacomit (Stiripentol)
      • Takhzyro (Lanadelumab)
      • Orfadin (Nitisinone)
      • Trikafta (elexacaftor, tezacaftor and ivacaftor)
      • Spinraza (Nusinersen)
      • Amondys 45 (Casimersen)
      • Voxzogo (Vosoritide)
      • Tepezza (Teprotumumab-trbw)
      • Isturisa (Osilodrostat)
      • Koselugo (Selumetinib)
      • VILTEPSO (Viltolarsen)
      • XERMELO (Telotristat)
      • BRINUERA(Cerliponase alfa)
      • MEPSEVII (Vestronidase)
      • PARSABIV (Etelcalcetide)
      • RADICAVA (Edaravone)
      • RHOPRESSA (Netarsudil)
    • Cardio
      • Vyndaqel (tafamidis meglumine)
    • MISC.
      • Brexafemme (Ibrexafungerp)
      • Qulipta Atogepant
      • Zemdri (Plazomicin)
      • Epidiolex (Cannabidiol)
      • ZAVICEFTA (Avibactum + Ceftazidime)
      • BAXDELA (Delafloxacin)
      • BEVYXXA (Betrixaban)
      • FASENRA (Benralizumab)
      • FIRAZYR (Icatibant)
      • KEVZARA(Sarilumab)
      • TRULANCE (Plecanatide)
      • VIVITROL (Naltrexone)
      • XADAGO (Safinamide)
      • Foscavir (Foscarnet sodium injection)
      • Anakinra (Kineret)
      • PADCEV (Enfortumab Vedotin-ejfv)
      • Lonsurf (Trifluridine/Tipiracil)
      • Dantrium IV (Dantrolene Sodium)
  • Blog
  • Contact Us

Triple-Negative Breast Cancer And their Treatment

Breast cancer is a type of cancer in which cells in the breast grow out of control. There are different kinds of breast cancer. The kind of breast cancer depends on which cells in the breast turn into cancer. Normal breast cells have receptors that respond to hormones such as estrogen and progesterone, which allows them to grow and regress in response to the hormone level. Hormone receptors may or may not be present in breast cancer. About two-thirds of breast cancers are “positive” and contain these receptors as normal breast cells do. 

 HER2/neu (hormone epidermal growth factor receptor 2) is a protein molecule that has a role in cell proliferation in normal cells. In some breast cancers, this protein is overly produced or “positive.” For HER2-positive tumours, there is a specific medication that targets this protein. Triple-negative breast cancers are not positive for estrogen receptors, progesterone receptors or HER2 protein. 

Signs and Symptoms

 The signs and symptoms of Triple-negative breast cancer are:

  • A new lump or mass
  • Swelling of all or part of a breast (even if no lump is felt)
  • Skin dimpling (sometimes looking like an orange peel)
  • Breast or nipple pain
  • Nipple retraction (turning inward)
  • Nipple or breast skin that is red, dry, flaking, or thickened
  • Nipple discharge (other than breast milk)
  • Swollen lymph nodes under the arm or near the collarbone (This can be a sign of breast cancer spreading even before the original tumour in the breast is large enough to be felt.)

 Note: Many of these symptoms can also be caused by non-cancerous breast conditions. Still, it’s essential to have any new breast mass, lump, or other change checked by an experienced healthcare professional so the cause can be found and treated if needed. 

 Treatment for Triple-negative breast cancer 

 Chemotherapy: Cells from the cancerous lump may have spread somewhere else in your body. The goal of chemotherapy is to kill those cancer cells wherever they may be. Chemotherapy lowers the chance that your cancer will grow or come back. 

 Surgery: In surgery, the surgeon removes the breast and nearby lymph nodes to see if cancer has spread.

 Radiation therapy: In such therapies, high-energy radiation is given to your breast to kill any remaining cancer cells.

Medication: There are medications for triple-negative breast cancer treatment, such as polymerase inhibitors or PARP inhibitors and immunotherapy medications, such as Trodelvy 180 mg injection, which contains Trodelvy is a type of drug called an antibody-drug conjugate (ADC). It consists of an antibody (an immune system protein) that’s linked to a chemotherapy drug. This medicine contains Sacituzumab govitecan hziy. 

Statistics: Triple-negative breast cancer in India and world

In the USA, according to the American Cancer Society Journals, a total of 1,151,724 breast cancer cases from 2010 through 2014 in the 39 states were identified in the data set, with a mean case age at diagnosis of 61.8 years. In this comprehensive collection of breast cancer cases, approximately 75% of the patients were NHW women; among all races/ethnicities, approximately 27.7% were diagnosed at a late stage, and around 5% were diagnosed at a distant stage. In the examined time period, TNBC cases accounted for 8.4% of all breast cancer cases. 

In India, according to the National Center for Biotechnology Information (NIH), seventeen cross-sectional studies involving 7,237 patients with breast cancer were included in the review of analysis made by NIH.14-30 Mean age of patients ranged from 43 to 55 years across studies, with a weighted average of age 50 years. 

Reference: https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/761115s000lbl.pdf

https://www.cdc.gov/cancer/breast/triple-negative.htm

https://www.cancer.org/cancer/breast-cancer/treatment/treatment-of-triple-negative.html

  • Posted by admin
  • On October 18, 2022
  • 0 Comments
  • 0 likes
Tags: trodelvy 180 mg vial, trodelvy 200 mg, trodelvy in india, trodelvy price in india

0 Comments

Leave Reply Cancel reply

You must be logged in to post a comment.

Archives
  • March 2023
  • February 2023
  • January 2023
  • December 2022
  • November 2022
  • October 2022
  • September 2022
  • August 2022
  • June 2022
  • May 2022
  • April 2022
  • March 2022
  • February 2022
  • January 2022
  • December 2021
  • October 2021
Categories
  • Achondroplasia (1)
  • acute lymphocytic leukemia (4)
  • Adrenal Cancer (1)
  • adrenal gland (1)
  • Bladder Cancer (3)
  • blood cancer (2)
  • Breast Cancer (9)
  • Chronic Lymphocytic Leukemia (2)
  • CMV (1)
  • Crohn’s disease (1)
  • DLBCL (1)
  • Drug & Cosmetic Act (1)
  • Enhertu (2)
  • hereditary tyrosinemia (1)
  • Hodgkin Lymphoma (4)
  • leukaemia (2)
  • Metastatic Breast Cancer (3)
  • metastatic colorectal cancer (2)
  • name patient import (1)
  • named patient program india (2)
  • NSCLC (1)
  • PNH (2)
  • RETEVMO (1)
  • rheumatoid arthritis (1)
  • Stomach Gastric Cancer (1)
  • T-cell Acute Lymphoblastic Leukaemia (1)
  • thyroid carcinoma (2)
  • Uncategorized (1)
Archives
  • March 2023
  • February 2023
  • January 2023
  • December 2022
  • November 2022
  • October 2022
  • September 2022
  • August 2022
  • June 2022
  • May 2022
  • April 2022
  • March 2022
  • February 2022
  • January 2022
  • December 2021
  • October 2021
Popular Posts
  • Understanding Rheumatoid Arthritis (RA)December 20, 2021
  • Nelarabine : Drug Information for PatientsOctober 29, 2021
  • Blincyto Treatment for Acute Lymphoblastic LeukemiaDecember 3, 2021
Photo Stream

Nelarabine : Drug Information for Patients

Previous thumb

Hodgkin's Lymphoma Treatment

Next thumb
Scroll

Indian Pharma Network helps in accessing new products in India. These products are launched and approved recently in USA or Europe but yet to be approved in India. We help in accessing these new launches through named patient import.

Quick Links
  • Home
  • About Us
  • Blog
  • Contact us
About Us

Indian Pharma Network facilitates patients connecting with genuine pharmaceutical suppliers, wholesalers and dealers.

Indian Pharma Network.
info@indianpharmanetwork.in
Corporate Office
Indian Pharma Network.
905 – 9th Floor, I-Thum Business Park,
Tower A, Plot no. A-40, Unit no. 5,
Sector-62, Noida 201301,
info@indianpharmanetwork.in
  • +91 9310090915

  • @2022 All Right Reserved indianpharmanetwork

    WhatsApp us

    • Home
    • About Us
    • Product List
      • ONCOLOGY
        • Cytalux (Pofalacianine)
        • Pylarify (Piflufolastat F18)
        • Truseltiq (Infigratinib)
        • Enhertu (Trastuzumab Deruxtecan)
        • Mektovi (Binimetinib)
        • Braftovi (Encorafenib)
        • Libtayo (Cemiplimab-rwlc)
        • Lorbrena (Lorlatinib)
        • Talzenna (Talazoparib)
        • Balversa (Erdafitinib)
        • Piqray (Alpelisib)
        • Alunbrig (Brigatinib)
        • Jemperli (Dostarlimab-gxly)
        • Tepmetko (Tepotinib)
        • COSELA (Trilaciclib)
        • Fotivda (Tivozanib)
        • Rozlytrek (Entrectinib)
        • Tivdak® (tisotumab vedotin-tftv)
        • Ayvakit (Avapritinib)
        • Tazverik (Tazemetostat)
        • Tukysa (Tucatinib)
        • Pemazyre (Pemigatinib)
        • Trodelvy (Sacituzumab govitecan-hziy)
        • Tabrecta (Capmatinib)
        • Retevmo (Selpercatinib)
        • Zepzelca (Lurbinectedin)
        • Gavreto (Pralsetinib)
        • MARGENZATM (margetuximab-cmkb)
        • Orgovyx (relugolix)
        • DANYELZA (naxitamab-gqgk)
        • ZEJULA (Niraparib)
        • VERZENIO (Abemaciclib)
        • TECENTRIQ (Atezolizumab)
        • NERLYNX (Neratinib)
        • Yervoy
        • CAPRELSA (Vandetnib)
        • CELSENTRI (Maraviroc)
        • CIDOFOVIR (Visitide)
        • IBRANCE (Palbociclib Capsules)
        • COMETRIQ (Cabozantinib)
        • CYRAMZA (Ramucirumab Injection)
        • DABRAFENIB (Tafinlar)
        • ENTEREG (Almiopan Capsule)
        • ERIVEDGE (Vismodegib Tablet)
        • LYNPARZA (Olaparib)
        • Qinlock (Ripretinib)
        • MEKINIST (Trametnib Tablet)
        • Mitotane (Lysodren)
        • NAVELBINE ORAL (Vinorelbine)
        • TEYSUNO (Tegafur)
        • ZELBORAF (Vemurafenib Tablet)
        • Zepzelca (Lurbinectedin)
        • ZYDELIG (Idelalisib)
      • HEMATOLOGY
        • Rezurock (Belumosudil)
        • Empaveli (Pegcetacoplan)
        • Idhifa (Enasidenib)
        • Besponsa (Inotuzumab Ozogamicin)
        • Tibsovo (Ivosidenib)
        • Poteligeo (Mogamulizumab-kpkc)
        • Xospata (Gilteritinib)
        • Asparlas (Calaspargase pegol-mknl)
        • Polivy (Polatuzumab Vedotin-piiqa
        • Reblozyl (Luspatercept–aamt)
        • Ukoniq (Umbralisib)
        • Pepaxto (Melphalan Flufenamide)
        • Zynlonta (Loncastuximab Tesirine-lpyl)
        • Rylaze
        • Exkivity (Mobocertinib)
        • SCEMBLIX®(Asciminib)
        • Besremi (Ropeginterferon alfa-2b-njft)
        • SARCLISA® (isatuximab-irfc)
        • Inqovi (decitabine and cedazuridine)
        • Blenrep (Belantamab Mafodotin-blmf)
        • Monjuvi (Tafasitamab-cxix)
        • TAFINLAR (Dabrafenib)
        • CALQUENCE (Acalabrutinib)
        • MYLOTARG Gemtuzumab
        • Aliqopa(Copanlisib)
        • Brentuximab Vedotin
        • AGRYLIN (Anagrelide Hydrochloride)
        • ATRIANCE (Nelarabine)
        • BLINCYTO (Blinatumomab)
        • ONCASPAR (Pegaspargase)
        • ERWINAZE (Asparaginase Erwinia Chrysanthemi)
        • FOLOTYN (Pralatrexate)
        • TREOSULFAN (Treosulfan)
        • Ponatinib
        • NPLATE (Romiplostim)
        • KYPROLIS (Carfilzomib)
        • MABCAMPATH (Alemtuzumab)
        • VENCLEXTA (Venetoclax)
        • SOLIRIS (eculizumab)
        • SYNRIBO (Omacetaxine Mepesuccinate)
        • ALKERAN (Melphalan)
        • FARYDAK (Panobinostat)
        • BOSULIF (Bosutinib)
        • ELDISINE (Vindesine Sulphate)
        • Ixazomib Citrate
        • TEPADINA (Thiotepa)
        • ZOLINZA (Vorinostat)
      • Nephrology
        • Ultomiris (Ravulizumab)
      • GASTROENTROLOGY
        • VOSEVI (Sofosbuvir, Velpatasvir, And Voxilaprevir)
        • OLYSIO (SIMEPREVIR)
        • SYPRINE (Trientine HCL)
      • NEUROLOGY
        • Azstarys (Serdexmethylphenidate and Dexmethylphenidate)
        • Qelbree (Viloxazine)
        • Lybalvi (Olanzapine and Samidorphan)
        • Aduhelm (aducanumab-avwa)
        • NUEDEXTA (Dextromethorphan Hydrobromide)
        • ILARIS (Canakinumab)
        • GLIOLAN (Aminolevulinic acid hydrochloride)
        • STELARA (Ustekinumab)
        • HUMIRA (Adalimumab)
      • IMMUNOLOGY
        • Ocrevus (Ocrelizumab)
        • Skyrizi (Risankizumab-rzaa)
        • PONVORY®(ponesimod)
        • Zeposia (Ozanimod)
        • SILIQ (Brodalumab)
        • TREMFYA (Guselkumab)
      • RARE DISEASES
        • Nulibry (Fosdenopterin)
        • Welireg (Belzutifan)
        • Xiaflex (Collagenase Clostridium Histolyticum)
        • Mepsevii (Vestronidase alfa-vjbk)
        • Symdeko (Tezacaftor/Ivacaftor & Ivacaftor)
        • Palynziq (Pegvaliase-pqpz)
        • Onpattro (Patisiran)
        • Galafold (Migalastat)
        • Diacomit (Stiripentol)
        • Takhzyro (Lanadelumab)
        • Orfadin (Nitisinone)
        • Trikafta (elexacaftor, tezacaftor and ivacaftor)
        • Spinraza (Nusinersen)
        • Amondys 45 (Casimersen)
        • Voxzogo (Vosoritide)
        • Tepezza (Teprotumumab-trbw)
        • Isturisa (Osilodrostat)
        • Koselugo (Selumetinib)
        • VILTEPSO (Viltolarsen)
        • XERMELO (Telotristat)
        • BRINUERA(Cerliponase alfa)
        • MEPSEVII (Vestronidase)
        • PARSABIV (Etelcalcetide)
        • RADICAVA (Edaravone)
        • RHOPRESSA (Netarsudil)
      • Cardio
        • Vyndaqel (tafamidis meglumine)
      • MISC.
        • Brexafemme (Ibrexafungerp)
        • Qulipta Atogepant
        • Zemdri (Plazomicin)
        • Epidiolex (Cannabidiol)
        • ZAVICEFTA (Avibactum + Ceftazidime)
        • BAXDELA (Delafloxacin)
        • BEVYXXA (Betrixaban)
        • FASENRA (Benralizumab)
        • FIRAZYR (Icatibant)
        • KEVZARA(Sarilumab)
        • TRULANCE (Plecanatide)
        • VIVITROL (Naltrexone)
        • XADAGO (Safinamide)
        • Foscavir (Foscarnet sodium injection)
        • Anakinra (Kineret)
        • PADCEV (Enfortumab Vedotin-ejfv)
        • Lonsurf (Trifluridine/Tipiracil)
        • Dantrium IV (Dantrolene Sodium)
    • Blog
    • Contact Us