Home » Orencia (Abatacept)
Orencia (Abatacept)
- Medicine Name: Orencia
- API: Abatacept
- Dosage Form & Strength: Injection: 250 mg/125 mg/75 mg/50 mg
- Manufactured By: Bristol-Myers Squibb
Orencia (abatacept) is a selective T-cell costimulation modulator, available as a lyophilized powder for intravenous (IV) administration in single-use vials of 250 mg and as a solution for subcutaneous (SC) administration in single-use syringes of 50, 75, and 125 mg or in autoinjectors of 125 mg/mL.for the treatment of:
- adult patients with moderately to severely active rheumatoid arthritis (RA).
- patients aged 2 years and older with moderately to severely active polyarticular juvenile idiopathic arthritis (pJIA).
- adult patients with active psoriatic arthritis (PsA).
- prophylaxis of acute graft versus host disease (aGVHD), along with a calcineurin inhibitor and methotrexate, in adults and pediatric patients aged 2 years and older undergoing hematopoietic stem cell transplantation (HSCT) from a matched or 1 allele-mismatched unrelated donor.
Limitations of Use: Concomitant use of Orencia (abatacept) with other immunosuppressives [e.g., Janus kinase (JAK) inhibitors, biologic disease-modifying antirheumatic drugs (bDMARDS)] is not recommended.
Recommended Dosage:
Intravenous Use for Adult RA and Adult PsA: In adults, abatacept may be given intravenously (at weeks 0, 2, 4, and then every 4 weeks) in doses based upon body weight ranging from 500 mg to 1000 mg.
Subcutaneous Use for Adult RA: Before the first subcutaneous dose, administer an optional loading dose as a single intravenous infusion as per the body weight categories above. Administer 125 mg by subcutaneous injection once weekly (within a day of the intravenous infusion if infusion is given). Patients switching from intravenous use to subcutaneous use, administer the first subcutaneous dose instead of the next scheduled intravenous dose.
Intravenous Use for pJIA in Pediatric Patients ≥6 Years Old: Pediatric patients weighing <75 kg administer 10 mg/kg intravenously and those weighing ≥75 kg administer the adult intravenous dosing regimen (not to exceed a maximum dose of 1,000 mg), as a 30-minute infusion. Subsequently, administer infusions at 2 and 4 weeks and every 4 weeks thereafter.
Subcutaneous Use for pJIA in Pediatric Patients ≥2 Years Old: Administer subcutaneously without an intravenous loading dose. For pediatric patients body weight of 10 kg to less than 25 kg, administer 50 mg. For pediatric patients body weight of 25 kg to less than 50 kg (once weekly), administer 87.5 mg (once weekly). For pediatric patients body weight of 50 kg or more, administer 125 mg (once weekly).
Subcutaneous Use for Adult PsA: Administer 125 mg by subcutaneous injection once weekly without an intravenous loading dose. Patients switching from intravenous use to subcutaneous use, administer first subcutaneous dose instead of next scheduled intravenous dose.
Intravenous Use for prophylaxis of aGVHD: For patients aged 6 years and older, administer at a 10 mg per kg dose (maximum dose 1,000 mg) as a 60-minute infusion on the day before transplantation, followed by a dose on Day 5, 14, and 28 after transplant. For patients aged 2 to less than 6 years, administer a 15 mg/kg dose as a 60 minute infusion on the day before transplantation, followed by a 12 mg/kg dose as a 60-minute infusion on Days 5, 14, and 28 after transplant.
- Concurrent treatment with Orencia injection and a TNF antagonist is not recommended. While transitioning from TNF antagonist therapy to Orencia therapy, patients should be monitored for signs of infection. Additionally, concomitant use of this drug with other biologic RA/PsA therapy or JAK inhibitors is not recommended.
- Serious infections, including sepsis and pneumonia, may occur in patients receiving Abatacept. Clinicians should exercise caution while using it in patients with a history of recurrent infections, underlying conditions that may predispose them to infections, or chronic, latent, or localized infections. Before initiating treatment, patients need to be screened for latent TB infection with a tuberculin skin test.
- Before initiating treatment with Abatacept in pediatric and adult patients, update vaccinations as per current vaccination guidelines. Live vaccines should not be administered concurrently with this treatment or within three months after discontinuation.
- Cytomegalovirus (CMV) invasive disease may occur in patients who received Orencia. Monitor them for CMV infection or reactivation for six months post-transplant regardless of the results of donor and recipient pre-transplant Cytomegalovirus (CMV) serology. Consider prophylaxis for CMV infection or reactivation.
What documents are required to import ORENCIA to India?
ORENCIA (abatacept) injections can be imported by patients or government hospitals on the name of the patients only.
The following documentation is required to import the product:
- A valid prescription from a qualified doctor.
- Patients diagnostic reports
- Patients ID proof (issued by the government of India)
How does the order be confirmed?
The order will be confirmed only after the receipt of:
- A valid prescription from Doctor
- Import permit if applicable
Is ORENCIA available in India?
ORENCIA (abatacept injection) is a (prescription drug, prescription medication, or prescription medicine) pharmaceutical drug that legally requires a medical prescription to be dispensed.
IPN (Indian Pharma Network) helps import cancer medicines on the named patient supply (NPS). Indian Pharma Network is the facilitator providing input
- On availability of Orencia in India (Mumbai, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore, Pune etc.)
- Medicine Price.
- Finding Genuine and reliable sources from the USA, Canada, Europe, and Australia
- Ensuring 100% transparency.
ORENCIA can be made available to patients, doctors, and hospitals in Mumbai, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore, Srinagar, Jammu, Jaipur, Chandigarh, Ludhiana, Noida, Gurgaon, Lucknow, and Pune and other cities in India. The order will be confirmed only after the receipt of a valid prescription from the doctor and an import permit.
IPN (Indian Pharma Network) can facilitate the supply of ORENCIA (prescription medicines) to all locations in the world and in India after fulfilling the legal requirement (if applicable).
Please contact +91-9310090915 | Toll-Free Number: 1800-889-1064 or write us at info@indianpharmanetwork.in for Orencia injection price in India.
We take to guarantee quality and delivery anywhere in the world as per the buyer’s requirements.
Indian Pharma Network is able to source the ORENCIA (Cancer Treatment Medicines) from across the globe and has the ability to supply. Indian Pharma offers its customers worldwide access to the best available treatment.
Indian Pharma Network (IPN) is able to dispense any valid prescription in the shortest possible time. All prescriptions are dispensed and checked by registered pharmacists and dispatched to the Patient’s address only from New Delhi, India.
What is the Generic Name for the trade name drug Orencia?
Abatacept is the Generic Name for the trade name drug Orencia.
What is the Manufacturer’s Name of Orencia?
Bristol-Myers Squibb Company manufactures Orencia.
Is Orencia approved by the FDA?
Yes. Orencia is approved by the US FDA. Date of first approval: December 23, 2005.
What strengths and dosage forms are available for Orencia?
Orencia is available in the following strengths and dosage forms:
- Intravenous Infusion: For injection: 250 mg lyophilized powder in a single-dose vial.
- Subcutaneous Use: Injection: 50 mg/0.4 mL, 87.5 mg/0.7 mL, and 125 mg/mL solution in single-dose prefilled syringes; and Injection: 125 mg/mL solution in a single-dose prefilled ClickJect™ autoinjector.
What are the most common side effects of Orencia?
The most common side effects reported with Orencia in patients with rheumatoid arthritis (RA) include upper respiratory tract infection, headache, nasopharyngitis, and nausea. In patients receiving Orencia for prophylaxis of acute graft-versus-host disease (aGVHD), commonly reported side effectns include pneumonia, anemia, hypertension, CMV reactivation or CMV infection, pyrexia, epistaxis, decreased CD4 lymphocytes, hypermagnesemia, and acute kidney injury.
What is the availability of Orencia near Medanta Hospital in Gurgaon?
Patients can buy Orencia near Medanta Hospital through a patient-specific import pathway. With a valid oncologist’s prescription, the treatment can be arranged and delivered directly to the hospital in Gurgaon.
What is the availability of Orencia in Bangalore?
Orencia in Bangalore is not yet commercially marketed, but patients can still access it through regulated import provisions. Once prescribed by a treating clinician, the medicine is sourced internationally and supplied to the treating hospital.
Is Orencia available at HCG Cancer, Bangalore?
Orencia may not be routinely stocked in India. However, it can be accessed through a Named Patient Program (NPP) with a valid prescription from an oncologist at the hospital. Indian Pharma Network (IPN) can help facilitate the import of Orencia at HCG Cancer, Bangalore.
What is the availability of Orencia in Mumbai?
Patient can access Orencia in Mumbai via special access programs that allow import of medicines approved in the global market, but unavailable in India. The treatment is delivered to the hospital where the patient is undergoing care.
I want to buy Orencia in Mumbai. How can I access it?
If you are looking to buy Orencia in Mumbai, the first step is consultation with your oncologist. Once prescribed, the medicine can be sourced from global suppliers through a compliant import process and delivered to your treating hospital.
What is the availability of Orencia in Chennai?
Patient access to Orencia in Chennai is possible through special access programs such as Named Patient Programs (NPP), which allow the import of internationally approved medicines. The treatment is arranged and delivered directly to the hospital where the patient is receiving care, ensuring compliance with regulatory requirements.
I want to buy Orencia in Chennai. How can I access it?
If you are looking to buy Orencia in Chennai, the first step is to consult your oncologist. Upon prescription, the medicine can be sourced from global suppliers through a compliant import process under NPP and delivered to your treating hospital, such as Apollo Hospitals or Cancer Institute (WIA).
What is the availability of Orencia in Hyderabad?
Orencia in Hyderabad is accessible through special access programs like Named Patient Programs (NPP), which enable the legal import of medicines not widely available in India. The medication is delivered directly to the hospital where the patient is undergoing treatment.
I want to buy Orencia in Hyderabad. How can I access it?
To buy Orencia in Hyderabad, patients should first consult their oncologist. Once prescribed, the medicine can be arranged through authorized channels under NPP guidelines and delivered to the treating hospital, such as Basavatarakam Indo-American Cancer Hospital.
I want to buy Orencia in Bangalore. How can I access it?
Patients seeking access to Orencia in Bangalore should consult their oncologist for evaluation and prescription. Following this, the medicine can be procured through compliant import channels and delivered to the treating hospital, such as HCG Cancer Centre, Bangalore.
Can I buy Orencia at major hospitals like Tata, KIMS, Apollo, or Fortis?
Orencia can be accessed at leading hospitals in India, such as Asian Institute of Immunology and Rheumatology (AIIR-NKDA), KIMS Hyderabad, Tata Memorial Centre, HCG, Apollo Hospitals, Fortis Healthcare, Max Healthcare, Rajiv Gandhi Cancer Institute & Research Centre, Manipal Hospitals, AIIMS, Medanta Hospital, and Kokilaben Dhirubhai Ambani Hospital, through the Named Patient Program (NPP) with a valid oncologist’s prescription. Indian Pharma Network assists with import and delivery to all these leading hospitals.
How does Orencia Import in India work?
Orencia Import in India is possible through the Named Patient Program. This means the medicine can be imported for a specific patient with a valid doctor’s prescription. Indian Pharma Network helps manage the complete process, including approvals and delivery, making sure the medicine reaches the patient safely and legally.
Who is a reliable Orencia supplier in India?
Indian Pharma Network is a trusted Orencia supplier in India, facilitating compliant access through global sourcing channels and structured documentation support for eligible patients under applicable regulatory provisions.
How much does Orencia cost in India?
Orencia is not yet approved in India. However, patients in India can legally access it through the Named Patient Program (NPP). Orencia prices may fluctuate over time because of market dynamics and regulatory changes. For the most transparent and latest Orencia cost in India, please call: +91 96548 60915, WhatsApp +91 98104 69557, or send an email to info@indianpharmanetwork.in.
Can Orencia be available in the SAARC countries?
Apart from Gulf countries, Orencia can be accessed through import provisions like the Named Patient Program (NPP) in SAARC countries (India, Afghanistan, Maldives, Nepal, Bangladesh, Bhutan, Pakistan, and Sri Lanka). Indian Pharma Network (IPN) can help facilitate the legal supply of Orencia in these countries. We help provide legal access to this therapeutic drug through our reliable channels.
Is it safe to buy Orencia online in India?
Yes, one can buy Orencia in India at the lowest price from the Indian Pharma Network (IPN) if this medicinal product is not yet registered or available in their country. We can help facilitate the supply of Orencia through legal channels.
Where can Orencia be shipped in India?
We can assist patients and healthcare providers in accessing Orencia across major cities and states in India through the Named Patient Program (NPP).
We can ship Orencia in Ahmedabad, Amritsar, Aurangabad, Bangalore, Bhopal, Bhubaneswar, Chandigarh, Chennai, Coimbatore, Dehradun, Delhi, Faridabad, Ghaziabad, Goa, Gurgaon, Guwahati, Hyderabad, Indore, Jaipur, Jammu Kashmir, Kanpur, Kochi, Kolkata, Lucknow, Ludhiana, Madurai, Mangalore, Mumbai, Mysore, Nagpur, Nashik, Navi Mumbai, Noida, Patna, Pune, Raipur, Ranchi, Surat, Thane, Trivandrum, Vadodara, Varanasi, Vijayawada, Visakhapatnam, and other cities across India.
Who is an authorized importer of Orencia in India?
Indian Pharma Network acts as the Orencia importer in India, assisting with Named Patient Import processes, regulatory documentation, and compliant international procurement for patients requiring this therapy.
In which countries is Orencia approved?
Orencia is approved and available in the United States, Europe, Canada, Japan, Australia, and China for the treatment of patients with rheumatoid arthritis (RA), polyarticular juvenile idiopathic arthritis (pJIA), psoriatic arthritis (PsA), and the prophylaxis of acute graft versus host disease (aGVHD).
Can I buy Orencia from Europe, the USA, or other countries?
Orencia is approved and available in several countries worldwide, including the United States, Europe, Canada, Japan, Australia, and China, but patients in India cannot buy it directly from the international market. It can be legally accessed through the Named Patient Program (NPP) with a valid prescription. Indian Pharma Network (IPN) assists with compliant sourcing and delivery to the treating hospital.
What are the storage conditions of Orencia?
Store Orencia in a refrigerator at 2°C to 8°C (36°F to 46°F) in its original package to protect it from light. The medication should not be frozen and should not be used beyond the expiration date mentioned on the vial, prefilled syringe, or autoinjector. Proper storage is important to maintain the stability and effectiveness.
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