Vyloy (Zolbetuximab-clzb)

Vyloy (zolbetuximab-clzb) is a claudin 18.2-directed cytolytic antibody and is used along with fluoropyrimidine- and platinum-containing chemotherapy for the first-line treatment of adults with locally advanced unresectable or metastatic HER2- gastric or gastroesophageal junction cancer whose tumors are claudin (CLDN) 18.2 positive.

Recommended Dosage: The recommended dosage of zolbetuximab-clzb is administered in combination with fluoropyrimidine- and platinum-containing chemotherapy. The initial dose is 800 mg/m² administered intravenously. For subsequent doses, administer 600 mg/m² every 3 weeks or 400 mg/m² every 2 weeks. Continue treatment until there is evidence of disease progression or unacceptable toxicity occurs.

• Treatment with this medicinal product may cause severe hypersensitivity reactions, including anaphylaxis. Monitor patients throughout and after the infusion. Stop treatment immediately in case symptoms like rash, breathing difficulty, or swelling occur. Provide relevant emergency medical treatment.
• Before starting each infusion of Vyloy 100 mg, pre-medicate patients with a combination of antiemetics (e.g., NK-1 receptor blockers and/or 5-HT3 receptor blockers, as well as other medicines as indicated) to prevent nausea and vomiting.
• In patients, receiving treatment with Vyloy 100 mg Infusion-related reactions, such as fever, chills, or low blood pressure, may occur. Slow or discontinue the infusion if symptoms appear. Premedicate instructed by your healthcare provider (HCP) to reduce the possibility of these reactions.
• This therapeutic drug can cause serious nausea and vomiting, which may lead to dehydration. Use anti-nausea medications as required. Monitor patients mainly during the initial phase of therapy, and ensure appropriate hydration to avoid complications.
• This medicine may harm an unborn baby. Women of childbearing potential should use effective contraception during treatment and for a specific period afterward. Pregnant patients should be aware of potential risks and consider alternative therapies when possible.
• It is not known if this medicine passes into breast milk. Because of potential risks to the infant, breastfeeding needs to be avoided during treatment and for a specified time after the last dose. Consult your clinician for guidance.

What documents are required to import VYLOY to India?

VYLOY (zolbetuximab-clzb) for injections can be imported by patients or government hospitals on the name of the patients only.

The following documentation is required to import the product:

• A valid prescription from a qualified doctor.
• Patients diagnostic reports
• Patient ID proof (issued by the government of India)

How does the order be confirmed?

• The order will be confirmed only after the receipt of:
• A valid prescription from the Doctor
• Import permit if applicable

Is VYLOY available in India?

VYLOY (zolbetuximab-clzb for injection) is a (prescription drug, prescription medication, or prescription medicine) pharmaceutical drug that legally requires a medical prescription to be dispensed.

IPN (Indian Pharma Network) helps import cancer medicines on the named patient supply (NPS). Indian Pharma Network is the facilitator providing input

• On availability of Vyloy in India (Mumbai, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore, Pune etc.)
• On availability in Gulf countries (Bahrain, Oman, Qatar, Kuwait, Iraq, Saudi Arabia, and the UAE).
• Medicine Price.
• Finding Genuine and reliable sources from the USA, Canada,
• Europe, and Australia
• Ensuring 100% transparency.

VYLOY can be made available to patients, doctors, and hospitals in Mumbai, Goa, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore, Srinagar, Jammu, Jaipur, Chandigarh, Ludhiana, Noida, Gurgaon, Lucknow, and Pune and other cities in India. The order will be confirmed only after the receipt of a valid prescription from the doctor and an import permit.

IPN (Indian Pharma Network) can facilitate the supply of VYLOY (prescription medicines) to all locations in the world and India after fulfilling the legal requirement (if applicable).

Please contact +91-9310090915 | Toll-Free Number: 1800-889-1064 or write us at info@indianpharmanetwork.in for Vyloy 100 mg injection price in India.

We guarantee quality and delivery anywhere in the world as per the buyer’s requirements.

Indian Pharma Network can source VYLOY (Cancer Treatment Medicines) from across the globe and can supply. Indian Pharma offers its customers worldwide access to the best available treatment.

Indian Pharma Network (IPN) can dispense any valid prescription in the shortest possible time. All prescriptions are dispensed and checked by registered pharmacists and dispatched to the Patient's address only from New Delhi, India.

What is the Generic Name for the trade name drug Vyloy®?

Zolbetuximab-clzb is a Generic Name for the trade name drug Vyloy®.

What is the Manufacturer's Name of Vyloy®?

Vyloy® is manufactured by Astellas Pharma US, Inc.

Is Vyloy® approved by the FDA?

Yes, Vyloy® is approved by the FDA. Date of first approval: October 18, 2024.

What is the dosage and form of Vyloy® supplied?

Vyloy is supplied for injection: 100 mg lyophilized powder in a single-dose vial for (IV) intravenous use.

What are the most common side effects of Vyloy®?

The most common side effects of Vyloy® in conjunction with mFOLFOX6 or CAPOX are nausea, vomiting, diarrhea, fatigue, decreased appetite, abdominal pain, peripheral sensory neuropathy, hypersensitivity reactions, constipation, decreased weight, and pyrexia.

How much does Vyloy® injection cost in India?

Prices of Vyloy injection may fluctuate over time due to market dynamics and regulatory changes. To get the correct details on Vyloy 100 mg injection cost in India, please Call/WhatsApp +91-9310090915 or send mail to info@indianpharmanetwork.in.

Can Vyloy® be available in SAARC countries?

Apart from Gulf countries, Vyloy® can be available in SAARC countries (India, Afghanistan, Maldives, Nepal, Bangladesh, Bhutan, Pakistan, and Sri Lanka). Indian Pharma Network (IPN) can help facilitate the legal supply of Vyloy® injections in these countries. We help ensure legal access to this therapeutic drug through our reliable channels.

Is it safe to buy Vyloy® injections online in India?

Yes, one can buy Vyloy 100 mg online in India at the lowest price from the Indian Pharma Network (IPN) if this medicinal product is not (yet) registered or available in their country. We can facilitate the supply of Vyloy® injections through legal channels.

What are the storage conditions of Vyloy® injections?

Store the vials refrigerated at temperatures 2 to 8°C (36 to 46°F) in the original carton. It is not advisable to freeze or shake it.