Lorbrena (Lorlatinib)

Lorbrena is a kinase inhibitor used for the treatment of adult patients with metastatic non-small cell lung cancer (NSCLC) whose tumors are anaplastic lymphoma kinase (ALK)-positive. 

Recommended Dosage: The recommended dosage of Lorbrena Tablets is 100 mg taken orally once daily, with or without food, until the disease is progressive or unacceptable toxicity occurs. Swallow tablets completely. It is not advisable to chew, crush or split them. Do not ingest in case the tablets are broken, cracked, or otherwise not intact. 

Take this medicine persistently each day. In case a dose is missed, then take the missed dose unless the next dose is due within four hours. Do not take a couple of doses at the same time in order to make up for a missed dose. Do not take any additional dose in case vomiting occurs after dosage but continue with the very next scheduled dose.

• A broad spectrum of CNS or central nervous system effects can emerge in patients receiving Lorbrena 25 mg. These include psychotic effects, seizures and changes in cognitive function, mood (including suicidal ideation), mental status, speech, and sleep.
• Boost in serum cholesterol and triglycerides can emerge in patients taking Lorlatinib. Initiate or boost the dose of lipid-reducing agents in those with hyperlipidemia. Assess serum cholesterol and triglycerides prior to initiating Lorlatinib, 1 and 2 months after initiating Lorlatinib, and periodically thereafter. 
• PR interval prolongation and atrioventricular (AV) block can appear in patients receiving Lorlatinib. Monitor ECG before initiating Lorlatinib and periodically thereafter. Withhold and resume at a lowered dose or at the same dose in those who undergo pacemaker placement. Permanently interrupt for recurrence in those without a pacemaker. 
• Severe or hazardous pulmonary adverse reactions consistent with ILD/pneumonitis can emerge with Lorlatinib. Promptly assess for ILD/pneumonitis in those who present with worsening of respiratory signs/symptoms indicative of ILD/pneumonitis (e.g., cough, dyspnea, and fever).
• Hypertension can appear in those receiving Lorlatinib 25 mg. Assess fasting serum glucose prior to starting Lorlatinib and evaluate periodically thereafter. Withhold and resume at a lowered dose or permanently interrupt treatment based on severity. 
• Based on data/findings and its mechanism of action, Lorlatinib can cause fetal harm if used by a pregnant woman. Females of reproductive age or potential should use an appropriate non-hormonal way of contraception. 

Indian Pharma Network is able to source the LORBRENA (Cancer Treatment Medicines) from across the globe, and has the ability to supply. Indian Pharma Network offers its customers worldwide access to the best available treatment.

Indian Pharma Network (IPN) is able to dispense any valid prescription in the shortest possible time. All prescriptions are dispensed and checked by registered pharmacists and dispatched to the Patient’s address only from New Delhi, India.

What is the Generic Name for the trade name drug Lorbrena?

Lorlatinib is Generic Name for the trade name drug Lorbrena®.

What is the Manufacturer Name of Lorbrena®?

Lorbrena® is manufactured by Pfizer Inc.

Is Lorbrena® approved by the FDA?

Yes, Lorbrena® is approved by the FDA. Date of first/initial approval: November 2, 2018.

What is the dosage and form of Lorbrena® supplied?

Lorbrena® is supplied as Tablets: 25 mg or 100 mg for oral administration. 

What are the most common side effects with Lorbrena®? 

Most common side effects with Lorbrena® include: cough, weight gain, cognitive effects, fatigue, peripheral neuropathy, edema, dyspnea, arthralgia, diarrhea, mood effects, hypercholesterolemia, and hypertriglyceridemia.

How much does Lorbrena® cost in India?

Lorbrena Cost in India is sensibly reasonable. In order to procure this NSCLC medication authentically, you can call or WhatsApp +91-9310090915 or send mail to info@indianpharmanetwork.in.

What are the storage conditions of Lorbrena®?

Store at 20°C to 25°C (68°F to 77°F); excursions permitted between temperature 15°C to 30°C (59°F to 86°F).

Where can I get Lorbrena® at the best price in India?

To get the best Lorbrena tablets price in India, you can connect with  Indian Pharma Network (IPN), or any other authorized Pharmaceutical Wholesaler Company which is certified by WHO-GDP and ISO 9001:2008. A medical prescription is required while buying Lorbrena.

Is it safe to buy Lorbrena® online from India? 

Yes, You can buy Lorbrena Tablets online from India authentically from https://www.indianpharmanetwork.in/ if Lorbrena is not available or has not been approved in your home country.

What are the Highlights of prescribing information for Lorbrena®?

Click Here to download full  Lorbrena prescribing information.