Kineret

Kineret (Anakinra 100 mg / 0.67 mL solution) is an interleukin-1 receptor antagonist used for: 

Rheumatoid Arthritis (RA): Reduction in signs and symptoms and resisting the progression of structural damage in moderately to severely active rheumatoid arthritis, in patients aged 18 years or older who have failed single/multiple disease modifying antirheumatic drugs (DMARDs). 

Cryopyrin-Associated Periodic Syndromes(CAPS): Treatment of Neonatal-Onset Multisystem Inflammatory Disease (NOMID). 

Kineret (Anakinra) is an FDA approved drug.

• Do not use kineret 100 mg in patients with known hypersensitivity to E coli-derived proteins, Kineret, or any other components of the product. 
• Administration of Kineret injection in combination with TNF blocking agents is not recommended. 
• Neutrophil counts should be assessed before initiating therapy with anakinra injection, and while on therapy, monthly for three months, and thereafter quarterly for a period up to one year.
• Treatment with anakinra drug should not be initiated in those patients who are with active infections. 

Indian Pharma Network is proficient in sourcing Kineret (Anakinra) injection from around the world and has the capability to supply it. We offer global access to the best available treatment for our customers worldwide in countries like Afghanistan, Bangladesh, Bhutan, India, Maldives, Nepal, Pakistan, and Sri Lanka.

Indian Pharma Network (IPN) is committed to dispensing any valid prescription promptly. All prescriptions are dispensed and verified by registered pharmacists and are dispatched only to the patient’s address. Your health and well-being are our top priorities

Indian Pharma Network helps you to connect with potential distributors, wholesalers, suppliers and dealers of Kineret in India. 

What is the Generic Name for the trade name drug Kineret® ?

Anakinra is Generic Name for the trade name drug Kineret®.

What is the Manufacturer Name of Kineret®?

Kineret® is manufactured by Swedish Orphan Biovitrum AB. 

When and by whom Kineret is approved?

Kineret was approved by the FDA in 2001.

What is the dosage and form of Kineret® available?

Kineret® is available as a 100 mg/0.67 mL solution for Subcutaneous Injection. 

What are the most commonly reported side effects of Kineret®? 

The most commonly reported kineret side effects (incidence ≥ 5%) when used for Rheumatoid Arthritis (RA) are injection site reaction, upper respiratory tract infection, worsening of rheumatoid arthritis, headache, diarrhea, nausea, sinusitis, arthralgia, abdominal pain and flu like-symptoms. 

The most commonly reported anakinra side effects in the first 6 months of treatment (incidence >10%) when used for Cryopyrin Associated Periodic Syndromes (CAPS) are headache, vomiting, injection site reaction, arthralgia, nasopharyngitis and pyrexia. 

What is the latest guidance on Kineret for COVID-19?

Kineret has been used in certain patients to treat COVID-19. For adults with severe COVID-19, the recommended dosage is 100 mg administered daily by subcutaneous injection for 10 days. However, it is crucial to follow your healthcare provider’s advice and continue other recommended preventive measures such as isolating, wearing a mask, and practicing hand hygiene.

Can Kineret be used for pediatric patients?

Yes, Kineret is used for pediatric patients, particularly those with Cryopyrin-Associated Periodic Syndromes (CAPS) and Deficiency of Interleukin-1 Receptor Antagonist (DIRA). For children aged one month and older, the initial dose is 1 to 2 mg/kg subcutaneously daily, with dose adjustments based on clinical response.

Is Kineret available in Asia?

Kineret (Anakinra) injection is available in Asian countries like Afghanistan, Bangladesh, Bhutan, India, Maldives, Nepal, Pakistan, and Sri Lanka. 

How can I get Kineret injection?

Indian Pharma Network (IPN) can facilitate the supply of Kineret (prescription medicine) to locations worldwide while adhering to legal requirements.

Are there any special storage instructions for Kineret?

Yes, Kineret should be stored in the refrigerator between 36°F to 46°F (2°C to 8°C). Do not freeze the medication. If necessary, Kineret can be kept at room temperature (below 77°F or 25°C) for up to 12 hours, but it should not be placed back in the refrigerator once it has reached room temperature.

Can Kineret be used with other medications?

Kineret can be used with other arthritis medications, such as methotrexate, steroids like prednisolone, and non-steroidal anti-inflammatory drugs (NSAIDs). However, it should not be used with TNF inhibitors like Enbrel®, Remicade®, or Humira®, due to an increased risk of infections.

What precautions should be taken before starting Kineret?

Before starting Kineret, inform your doctor if you have any infections, a history of tuberculosis (TB), or if you are taking other medications that affect the immune system. A TB test is often required before initiating treatment. Also, discuss any history of cancer or plans to become pregnant with your doctor.

Where is Kineret available in India?

Kineret available in India (Noida, Delhi, Mumbai, Gurgaon, Lucknow,  Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore and Pune etc