Vosevi (Sofosbuvir, Velpatasvir and Voxilaprevir)
- Medicine Name: Vosevi
- API: Sofosbuvir, Velpatasvir and Voxilaprevir
- Dosage Form & Strength: Tablets: 400 mg sofosbuvir, 100 mg velpatasvir, and 100 mg voxilaprevir
- Manufactured By: Gilead Sciences, Inc.
Vosevi (sofosbuvir, velpatasvir, and voxilaprevir) is a fixed-dose combination medicine of a nucleotide analog NS5B polymerase inhibitor (SOF), a pangenotypic NS5A inhibitor (VEL), and a pangenotypic NS3/4A protease inhibitor (VOX). It is used for the treatment of genotype 1-6 chronic hepatitis C virus (HCV) infection.
Vosevi is indicated for the treatment of adult patients with chronic HCV infection without cirrhosis or with compensated cirrhosis (Child-Pugh A) who have:
- genotype 1, 2, 3, 4, 5, or 6 infection and have previously been treated with an HCV regimen containing an NS5A inhibitor.
- genotype 1a or 3 infection and have previously been treated with an HCV regimen containing sofosbuvir without an NS5A inhibitor.
Recommended Dosage:
The recommended dosage of Vosevi is one tablet, taken orally, once daily with food. One tablet of Vosevi mainly contains 400 mg of sofosbuvir, 100 mg of velpatasvir, and 100 mg of voxilaprevir. Below is the recommended treatment regimen and duration based on the patient population.
- Genotypes 1, 2, 3, 4, 5, or 6: If previously treated with a regimen that included an NS5A inhibitor, the recommended treatment duration is 12 weeks.
- Genotypes 1a or 3: If previously treated with Sofosbuvir but without an NS5A inhibitor, the recommended treatment duration is 12 weeks.
This medicine is not recommended in patients with moderate or severe hepatic impairment (Child-Pugh B or C) because of higher exposures of voxilaprevir in these patients.
- Reactivation of the Hepatitis B Virus has occurred post anti-viral treatment in patients who have co-infected Hepatitis B & C. Hepatitis B testing is required before the initiation of treatment, and adverse effects due to anti-viral treatment should be monitored.
- Reactivation of hepatitis B can cause serious liver complications, including liver failure and death in rare cases. Doctors may start hepatitis B treatment if needed and monitor liver function closely throughout and after completing therapy.
- When you take amiodarone with sofosbuvir-containing medications like Vosevi, severe cases of slow heart rate (symptomatic bradycardia) can occur. Some people have died from serious heart complications, and some have needed to have pacemakers surgically implanted.
- Medicines that strongly induce P-glycoprotein (P-gp) or certain liver enzymes called CYP may reduce the levels of medicine in the blood. This may reduce the effectiveness of treatment and increase the risk of hepatitis C treatment failure.
- If amiodarone must be used with Vosevi, close heart monitoring is required, especially during the first few days of treatment. Patients should immediately report symptoms such as dizziness, fainting, weakness, chest pain, or shortness of breath to a healthcare provider.
- Women of childbearing age should let their healthcare provider know if they are pregnant or looking to become pregnant before starting treatment. Doctors may discuss alternative treatment timing based on individual health conditions and medical requirements.
- Females who are breastfeeding should consult their clinician before starting treatment. The doctor will assess whether to continue breastfeeding or discontinue the medicine, considering the importance of treatment for the mother.
What documents are required to import VOSEVI to India?
VOSEVI (Sofosbuvir, Velpatasvir and Voxilaprevir) tablets can be imported by patients or government hospitals in the name of the patients only.
The following
- documentation is required to import the product:
- A valid prescription from a qualified doctor.
- Patients diagnostic reports
- Patient ID proof (issued by the government of India)
How does the order get confirmed?
The order will be confirmed only after the receipt of:
- A valid prescription from the Doctor
- Import permit if applicable
Is VOSEVI available in India?
VOSEVI (sofosbuvir, velpatasvir and voxilaprevir tablets) is a (prescription drug, prescription medication, or prescription medicine) pharmaceutical drug that legally requires a medical prescription to be dispensed.
IPN (Indian Pharma Network) helps import cancer medicines on the named patient supply (NPS). Indian Pharma Network is the facilitator, providing input
- On the availability of Vosevi in India (Mumbai, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore, Pune, etc.)
- On availability in Gulf countries (Bahrain, Oman, Qatar, Kuwait, Iraq, Saudi Arabia, and the UAE).
- Vosevi price in India.
- Finding Genuine and reliable sources from the USA, Canada, Europe, and Australia
- Ensuring 100% transparency.
VOSEVI can be made available to patients, doctors, and hospitals in Mumbai, Goa, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore, Srinagar, Jammu, Jaipur, Chandigarh, Ludhiana, Noida, Gurgaon, Lucknow, and Pune, and other cities in India. The order will be confirmed only after the receipt of a valid prescription from the doctor and an import permit.
IPN (Indian Pharma Network) can facilitate the supply of VOSEVI (prescription medicines) to all locations in the world and India after fulfilling the legal requirements (if applicable).
Please contact +91-9810469557 | Toll-Free Number: 1800-889-1064 or write us at info@indianpharmanetwork.in for Vosevi cost in India.
We guarantee quality and delivery anywhere in the world as per the buyer’s requirements.
Indian Pharma Network can source VOSEVI (Cancer Treatment Medicines) from across the globe and can supply. Indian Pharma offers its customers worldwide access to the best available treatment.
Indian Pharma Network (IPN) can dispense any valid prescription in the shortest possible time. All prescriptions are dispensed and checked by registered pharmacists and dispatched to the Patient’s address only from New Delhi, India.
What is the Generic Name for the trade name drug Vosevi?
Sofosbuvir, Velpatasvir, and Voxilaprevir are the generic names for Vosevi.
What is the Manufacturer’s Name of Vosevi?
Vosevi is manufactured by Gilead Sciences, Inc.
Is Vosevi approved by the FDA?
Yes. Vosevi is approved by the FDA. Date of first approval: July 18, 2017.
What is the dosage and form of Vosevi supplied?
Vosevi is supplied as Tablets: 400 mg sofosbuvir, 100 mg velpatasvir, and 100 mg voxilaprevir for oral use.
What are the most common side effects of Vosevi Tablets?
The most commonly reported side effects of Vosevi are headache, diarrhea, fatigue, and nausea.
How does Vosevi Import in India work?
Vosevi Import in India is possible through the Named Patient Program. This means the medicine can be imported for a specific patient with a valid doctor’s prescription. Indian Pharma Network helps manage the complete process, including approvals and delivery, making sure the medicine reaches the patient safely and legally.
How much does Vosevi Tablet cost in India?
Vosevi is not yet approved in India. However, patients in India can legally access it through the provision called the Named Patient Program (NPP). Vosevi prices may fluctuate over time because of market dynamics and regulatory changes. For the most transparent and latest Vosevi cost in India, please call/WhatsApp +91 98104 69557 or send an email to info@indianpharmanetwork.in.
Can Vosevi Tablets be available in SAARC countries?
Apart from Gulf countries, Vosevi can be accessed through import provisions like the Named Patient Program (NPP) in SAARC countries (India, Afghanistan, Maldives, Nepal, Bangladesh, Bhutan, Pakistan, and Sri Lanka). Indian Pharma Network (IPN) can help facilitate the legal supply of Vosevi tablets in these countries. We help provide legal access to this therapeutic drug through our reliable channels.
Is it safe to buy Vosevi Tablets online in India?
Yes, one can buy Vosevi in India at the lowest price from the Indian Pharma Network (IPN) if this medicinal product is not yet registered or available in their country. We can help facilitate the supply of Vosevi tablets through legal channels.
What are the storage conditions of Vosevi Tablets?
Store the tablets of Vosevi (sofosbuvir, velpatasvir, and voxilaprevir) below 30 °C (86 ºF). Dispense only in the original container.
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