Zokinvy (Lonafarnib)

Zokinvy (lonafarnib) is the first and only approved therapeutic drug to target the cause and symptoms of Progeria, also called Hutchinson-Gilford Progeria Syndrome (HGPS), and processing-deficient Progeroid Laminopathies (PDPL) in young individuals aged 12 months and older. HGPS and PDPL are caused when the body develops harmful proteins: progerin and progerin-like proteins.
When used for Progeroid Laminopathies, Zokinvy 50 mg/75 mg capsule is only for those Progeroid Laminopathies associated with the production of these harmful irregular (progerin-like) proteins.

Recommended Dosage: The recommended starting dosage of Lonafarnib for patients with a BSA of 0.39 m2 and more is 115 mg/m2 taken twice daily with morning and evening meals to lower the probability of gastrointestinal side effects. An appropriate dosage strength does not exist for patients with a BSA of less than 0.39 m2.
After four months of treatment, the dosage of Lonafarnib can be increased to 150 mg/m2 twice daily with morning and evening meals. When calculating the total daily dose, make sure to round it to the nearest 25 mg.
In case of a missed/skipped dose, try to take it as quickly as you can with food, but only if there are more than 8 hours left before your next scheduled dose. If not more than 8 hours remain, just skip the missed dose and continue with your regular dosing schedule.

• Treatment with Lonafarnib 50 mg/75 mg may prolong the QTc interval, increasing the risk of life-threatening heart arrhythmias. Regular ECG monitoring is required, mainly if used with medicines known to prolong QTc or in individuals with known heart conditions.
• Certain therapeutic drugs may interfere with Lonafarnib’s effectiveness or increase side effects. Avoid strong CYP3A inhibitors and inducers. Let your doctor know about all medicines, including over-the-counter drugs, to ensure safe and effective use.
• This therapeutic drug may cause kidney damage, mainly in those with pre-existing kidney issues. Routine kidney function tests and monitoring of hydration levels are essential during treatment for the prevention of potential renal complications.
• Prolonged use of this medicinal product may affect vision due to retinal toxicity. Patients should undergo regular eye examinations and quickly report any visual changes, such as blurred vision or difficulty seeing, to their doctor.
• Lonafarnib may impact fertility in both males and females. Patients planning to conceive should discuss probable risks and alternative existing options with their doctor before starting therapy, as the effects on long-term fertility remain uncertain.
  Treatment with this medicine can harm an unborn baby. Women of childbearing age should use effective contraception during therapy and for at least one month after stopping the medication. Inform your doctor promptly if you suspect pregnancy while taking this medicine.

What documents are required to import ZOKINVY to India?

ZOKINVY (lonafarnib) capsules can be imported by patients or government hospitals on the name of the patients only.
The following documentation is required to import the product:

• A valid prescription from a qualified doctor.
• Patients diagnostic reports
• Patient ID proof (issued by the government of India)

How does the order be confirmed?

The order will be confirmed only after the receipt of:

• A valid prescription from the Doctor
• Import permit if applicable

Is ZOKINVY available in India?

ZOKINVY (lonafarnib capsules) is a (prescription drug, prescription medication, or prescription medicine) pharmaceutical drug that legally requires a medical prescription to be dispensed.

IPN (Indian Pharma Network) helps import cancer medicines on the named patient supply (NPS). Indian Pharma Network is the facilitator providing input

• On availability of Zokinvy in India (Mumbai, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore, Pune etc.)
• On availability in Gulf countries (Bahrain, Oman, Qatar, Kuwait, Iraq, Saudi Arabia, and the UAE).
• Medicine Price.
• Finding Genuine and reliable sources from the USA, Canada, Europe, and Australia
• Ensuring 100% transparency.

ZOKINVY can be made available to patients, doctors, and hospitals in Mumbai, Goa, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore, Srinagar, Jammu, Jaipur, Chandigarh, Ludhiana, Noida, Gurgaon, Lucknow, and Pune and other cities in India. The order will be confirmed only after the receipt of a valid prescription from the doctor and an import permit.

IPN (Indian Pharma Network) can facilitate the supply of ZOKINVY (prescription medicines) to all locations in the world and India after fulfilling the legal requirement (if applicable).

Please contact +91-9310090915 | Toll-Free Number: 1800-889-1064 or write us at info@indianpharmanetwork.in for Zokinvy 50 mg/75 mg Capsules price in India.

We guarantee quality and delivery anywhere in the world as per the buyer’s requirements.

Indian Pharma Network can source the ZOKINVY (Cancer Treatment Medicines) from across the globe and can supply. Indian Pharma offers its customers worldwide access to the best available treatment.

Indian Pharma Network (IPN) can dispense any valid prescription in the shortest possible time. All prescriptions are dispensed and checked by registered pharmacists and dispatched to the Patient's address only from New Delhi, India.

What is the Generic Name for the trade name drug Zokinvy®?

Lonafarnib is a Generic Name for the trade name drug Zokinvy®.

What is the Manufacturer's Name of Zokinvy®?

Zokinvy® is manufactured by Sentynl Therapeutics, Inc.

Is Zokinvy® approved by the FDA?

Yes, Zokinvy® is approved by the FDA. Date of first approval: August 7, 2020.

What is the dosage and form of Zokinvy® supplied?

Zokinvy® is supplied in Capsules: of 50 mg and 75 mg for oral use.

What are the most common side effects of Zokinvy®?

The most common side effects of Zokinvy® are vomiting, diarrhea, decreased appetite, nausea, weight loss, constipation, muscle and joint (musculoskeletal) pain, infection, stomach-area (abdominal) pain, tiredness, increased liver enzyme blood test results

How much does Zokinvy® (Lonafarnib) Capsules cost in India?

Prices of Zokinvy may vary over time due to market dynamics and regulatory changes. To get the accurate and latest information on Zokinvy 50 mg/75 mg cost in India, kindly Call/WhatsApp +91-9310090915 or send mail to info@indianpharmanetwork.in.

Can Zokinvy® be available in SAARC countries?

Apart from Gulf countries, Zokinvy® can be available in SAARC countries (India, Afghanistan, Maldives, Nepal, Bangladesh, Bhutan, Pakistan, and Sri Lanka). Indian Pharma Network (IPN) can help facilitate the supply of Zokinvy® Capsuless in these countries, ensuring access to this therapeutic drug through legal and reliable channels.

Is it safe to buy Zokinvy® Capsules online in India?

Yes, one can buy Zokinvy 50 mg/75 mg online in India at the lowest price from the Indian Pharma Network (IPN) if this medicinal product is not (yet) registered or available in their country. We can help facilitate the supply of Zokinvy® Capsules through legal channels.

What are the storage conditions of Zokinvy® Capsules?

Store this therapeutic drug at 20 to 25°C (68 to 77°F), with excursions permitted to 15 to 30°C (59 to 86°F).