Zemdri (Plazomicin)

Zemdri injection is an aminoglycoside antibacterial used in patients aged 18 years or older for the treatment of complicated urinary tract infections (cUTI), including pyelonephritis caused by the following susceptible microorganism(s): Klebsiella pneumoniae, Escherichia coli, Enterobacter cloacae and Proteus mirabilis. 

Recommended Dosage: The recommended dosage regimen of Zemdri injection is 15 mg/kg given or administered every 24 hours by intravenous (IV) infusion over 30 minutes in patients aged 18 years or older and with CLcr (creatinine clearance) ≥ 90 mL/min. Time-span of therapy should be guided as per severity of infection as well as patient’s clinical status for up to 1-week (7 days). Throughout the therapy, dosage adjustments may be needed depending on the change in renal function.

• Nephrotoxicity may occur with the use of Plazomicin. Evaluate CLcr prior to starting therapy and daily throughout therapy, particularly in those at higher risk of nephrotoxicity, such as those with renal impairment, the elderly, and those on concomitant potentially nephrotoxic medicines. In case of worsening renal function, the benefit of continuing Plazomicin Injection should be assessed. 
• Ototoxicity, manifested as hearing loss, tinnitus, or vertigo, may occur with Zemdri. Aminoglycoside-associated ototoxicity may occur primarily in those with a family history of hearing loss (excluding age-related hearing loss), those with renal impairment, and in those receiving higher doses or for longer periods than required.
• Aminoglycosides may be linked with exacerbation of muscle weakness in those with underlying neuromuscular disorders, or delay in recovery of neuromuscular function in those receiving concomitant neuromuscular blocking agents. During therapy, monitor for side effects linked with neuromuscular blockade, particularly in high-risk patients, such as those with underlying neuromuscular disorders or those concomitantly receiving neuromuscular blocking agents.
• Aminoglycosides, including Zemdri 500 mg, can cause fetal harm if administered to a pregnant woman. Aminoglycosides cross the placenta, and streptomycin may be linked with several reports of total, irreversible, bilateral congenital deafness in pediatric patients exposed in utero. Patients who use Zemdri during pregnancy, or become pregnant while taking this medicine should be apprised of the potential hazard to the fetus. 
• Severe and occasionally fatal hypersensitivity (anaphylactic) reactions may occur in patients receiving aminoglycoside antibacterial medicines. Before therapy with Plazomicin is instituted, watchful inquiry about previous hypersensitivity reactions to other aminoglycosides should be made.
• Clostridium difficile-associated diarrhea (CDAD) may occur for almost all systemic antibacterial medicines and may range in severity from mild diarrhea to fatal colitis. Therapy with antibacterial medicines alters the normal flora of the colon and may permit overgrowth of C. difficile. In case Clostridium difficile-associated diarrhea is suspected or confirmed, antibacterial medicines not directed against C. difficile should be discontinued. Manage fluid and electrolyte levels, supplement protein intake, assess antibacterial treatment of C. difficile, and institute surgical assessment.
• Prescribing Zemdri medicine in the absence of a proven or strongly suspected bacterial infection is unlikely to offer benefit to the patient and increases the probability of the development of drug-resistant bacteria.

What documents are required to import ZEMDRI to India?

ZEMDRI (Plazomicin) Injections can be imported by patients or government hospitals on the name of the patients only. 

The following documentation required to import the product:

• Valid prescription from a qualified doctor.
• Patients diagnostic reports
• Patients Identity Proof (issued by government of India)

How does order be confirmed?

The order will be confirmed only after the receipt of:

• Valid prescription of Doctor
• Import permit if applicable

Is ZEMDRI available in India?

ZEMDRI (Plazomicin Injection) is a (prescription drug, prescription medication or prescription medicine) pharmaceutical drug that legally requires a medical prescription to be dispensed.

IPN (Indian Pharma Network) helps import cancer medicines on the named patient supply (NPS). Indian Pharma Network is facilitator providing input

• On availability of Zemdri in India (Delhi, Mumbai, Kolkata, Hyderabad, Chennai, Ahmedabad, Pune, and Bangalore etc.)
• Medicine Price.
• Finding Genuine and reliable source from Canada, Europe, USA and Australia
• Ensuring 100% transparency.

ZEMDRI can be made available to patients, doctors and hospitals at Mumbai, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore, Srinagar, Jammu, Jaipur, Chandigarh, Ludhiana, Noida, Gurgaon, Lucknow and Pune and other cities in India. The order will be confirmed only after the receipt of a valid prescription from the doctor and import permit.

IPN (Indian Pharma Network) can facilitate the supply of ZEMDRI (prescription medicines) to all locations in the world and in India after fulfilling the legal requirement (if applicable). 

Please contact +91-9310090915 | Toll-Free Number: 1800-889-1064 or write us at info@indianpharmanetwork.in for Zemdri 500 mg/10 mL price in India. 

We take guarantee of quality and delivery anywhere in the world as per the buyer’s requirements.

Indian Pharma Network is able to source the ZEMDRI (Cancer Treatment Medicines) from across the globe, and has the ability to supply. Indian Pharma Network offers its customers worldwide access to the best available treatment.

Indian Pharma Network is able to dispense any valid prescription in the shortest possible time. All prescriptions are dispensed and checked by registered pharmacists and dispatched to the Patient’s address only from New Delhi, India.

What is the Generic Name for the trade name drug Zemdri®?

Plazomicin is Generic Name for the trade name drug Zemdri®.

What is the Manufacturer Name of Zemdri®?

Zemdri® is manufactured by Achaogen, Inc.

Is Zemdri® approved by the FDA?

Yes, Zemdri® is approved by the FDA. Date of first/initial approval: June 25, 2018.

Where can I get Zemdri® at the best price in India?

To get the best Zemdri price in India, contact Indian Pharma Network (WHO-GDP and ISO 9001 : 2008 authorized Company). A medical prescription is required while buying Zemdri®.

What is the dosage and form of Zemdri® supplied?

Zemdri® is supplied as Injection 500 mg/10 mL (50 mg/mL) for intravenous administration. 

What are the most common side effects with Zemdri®? 

The most common side effects with Zemdri® include: decreased renal function, diarrhea, hypertension, 

headache, nausea, vomiting and hypotension.

How much does Zemdri® cost in India?

The zemdri cost in India is less and can vary. In order to procure this cUTI medication authentically, you can Call/WhatsApp +91-9310090915 or send mail to info@indianpharmanetwork.in.

What are the storage conditions of Zemdri®?

Store Zemdri 500 mg/10 mL (50 mg/mL) refrigerated at 2°C to 8°C (36°F to 46°F).

Is it safe to buy Zemdri® online from India? 

Yes, You can buy Zemdri injection online in India at the best price from Indian Pharma Network if Zemdri® has not been approved or is not available in your country.

What are the Highlights of prescribing information for Zemdri®?

Click Here to download full  zemdri prescribing information.