Vonjo (Pacritinib)

Vonjo is a kinase inhibitor indicated for the treatment of adults with intermediate or high-risk primary or secondary myelofibrosis (post-polycythemia vera or post-essential thrombocythemia) when they have a platelet count below 50 x 10^9/L. This indication is granted under accelerated approval based on spleen volume reduction. Continued approval may be contingent upon verification of clinical benefit in confirmatory trials.

Recommended Dosage

• Recommended dosage: 200 mg orally twice daily.
  
• May be taken with or without food.
  

• hemorrhage: Avoid use in patients with active bleeding and hold Vonjo before planned surgical procedures. May require dose interruption, reduction, or discontinuation depending on severity.
• Diarrhea: Manage significant diarrhea with anti-diarrheals, dose reduction, or interruption.
• Thrombocytopenia: Manage by dose reduction or interruption.
• Prolonged QT Interval: Avoid use in patients with a baseline QTc >480 msec. 
• Adjust dosage in patients with a QTcF >500 msec. Correct hypokalemia during Vonjo administration.
• Major Adverse Cardiac Events (MACE): Monitor patients with cardiovascular risk factors. 
• Evaluate and treat promptly if signs appear.Thrombosis: 
• Monitor for and treat deep venous thrombosis, pulmonary embolism, and arterial thrombosis promptly.
• Secondary Malignancies: Past/current smokers may be at increased risk of lymphoma and other malignancies.
• Risk of Infection: Delay treatment until active serious infections resolve. 
• Manage signs of infection promptly.

If you are interested in importing Vonjo (Pacritinib) to India, here is a comprehensive guide on the documentation and availability of this medication:

Required Documentation for Import: Vonjo (Pacritinib) can be imported to India by patients or government hospitals under the patient’s name. The following documentation is necessary for the import process:

• A valid prescription from a qualified doctor.
  
• Patient’s diagnostic reports.
  
• Patient’s government-issued ID proof.

Order Confirmation: The order for Vonjo will be confirmed only upon the submission of the following documents:

• A valid prescription from a qualified doctor.
  
• An import permit if it is applicable to your case.

Availability in India: Vonjo (Pacritinib) is a prescription medication, which means it legally requires a medical prescription for dispensing. To check its availability in India and access the product, you can rely on Indian Pharma Network (IPN).

Indian Pharma Network (IPN) is experienced in importing various medicines, including cancer treatments, through the Named Patient Supply (NPS) process. It serves as a facilitator that provides critical assistance in the following areas:

• Verifying medicine availability in various locations across the world, including India.
  
• Offering transparent information on medicine prices.
  
• Sourcing genuine and reliable sources from the USA, Canada, Europe, and Australia.
  
• Ensuring 100% transparency in the procurement process.

Indian Pharma Network takes pride in ensuring quality and timely delivery of medicines worldwide to meet the specific requirements of buyers.

Indian Pharma Network is able to source the ACCRUFER (Cancer Treatment Medicines) from across the globe and has the ability to supply. Indian Pharma offers its customers worldwide access to the best available treatment.

Indian Pharma Network is able to dispense any valid prescription in the shortest possible time. All prescriptions are dispensed and checked by registered pharmacists and dispatched to the Patient’s address only from New Delhi, India.

What is Vonjo (Pacritinib) used for?

Vonjo is a medication used for the treatment of adults with intermediate or high-risk primary or secondary myelofibrosis with a platelet count below 50 × 10^9/L. This includes cases of post-polycythemia vera or post-essential thrombocythemia.

Is Vonjo FDA approved?

Yes, Vonjo got approved by the FDA in 2022.

How is Vonjo administered?

The recommended dosage of Vonjo is 200 mg taken orally twice daily. It can be taken with or without food.

What are the common side effects of Vonjo?

Common side effects of Vonjo include diarrhea, thrombocytopenia, nausea, anemia, and peripheral edema.