Fexinidazole Tablets

Fexinidazole is a nitroimidazole antimicrobial, used for the treatment of both first-stage (hemolymphatic) and second-stage (meningoencephalitic) human African trypanosomiasis (HAT) due to Trypanosoma brucei gambiense in those aged 6 years and older and weighing at least 20 kg.

Due to the decreased efficacy observed in those with severe second-stage HAT (cerebrospinal fluid WBC count (CSF-WBC) >100 cells/µL) due to T. brucei gambiense disease, Fexinidazole should only be used in these patients if there are no other existing treatment options.

Recommended Dosage: Fexinidazole tablets are intended to be administered once daily for a total of days (loading + maintenance dose) with food each day at about the same time of the day. Neither break nor crush the tablets. The recommended dosage of Fexinidazole for patients aged 6 years and older and weighing at least 20 kg is as per body weight.

The recommended daily dose for body weight greater than or equal to 35 kg:

• Loading dose: 1,800 mg (3 tablets of 600 mg daily) for 4 days
• Maintenance dose: 1,200 mg (2 tablets of 600 mg daily) for 6 days

The recommended daily dose for body weight greater than or equal to 20 kg to less than 35 kg:

• Loading dose: 1,200 mg (2 tablets of 600 mg daily) for 4 days
• Maintenance dose: 600 mg (1 tablet of 600 mg daily) for 6 days

In case the first event of puking occurs after taking pills of Fexinidazole, do not re-dose. Take the next dose the following day considering the recommended treatment schedule. In case a scheduled dose is missed (not taken on the assigned day), resume normal dosing the following day until the complete course  (10 days) of treatment has been completed.

• The fexinidazole 600 tablets are not for patients with known hypersensitivity to this medicine or any nitroimidazole class of medicines (such as metronidazole, or tinidazole).
• Fexinidazole tablets have been known to prolong the QT interval in a concentration-dependent manner. This treatment caused an average increase of 19 msec in the QTcF interval. 
• Those with QTcF interval beyond 470 msec, uncorrected hypokalemia, and a known history of torsade de pointes, congenital long QT syndrome, cardiac arrhythmias, uncompensated heart failure, or family history of sudden death should avoid using this medicine. 
• Neutropenia may occur in those with Fexinidazole treatment. Avoid concomitant use of drugs that may cause neutropenia and assess leukocyte count periodically. Precisely monitor those with neutropenia for fever or other symptoms and treat promptly if such symptoms occur.
• Elevations in liver transaminases may occur. Assess liver-associated laboratory tests at the start and during treatment with Fexinidazole. Monitor those who develop abnormal liver-associated laboratory tests during treatment with this medicine.
• Nitroimidazole-class medicines may cause a disulfiram-like reaction characterized by vomiting, rash, abdominal cramps, nausea, flushing, weakness, and headache in those who concurrently consume alcohol. Do not consume alcoholic beverages throughout treatment with Fexinidazole and for at least 48 hours after completing therapy.
• Psychotic reactions may occur in those who are concurrently taking medicine nitroimidazole and disulfiram. Those who have taken these medicines within the last couple of weeks should avoid using Fexinidazole.

What documents are required to import FEXINIDAZOLE to India?

FEXINIDAZOLE tablets can be imported by patients or government hospitals on the name of the patients only. 

The following documentation is required to import the product:

• A valid prescription from a qualified doctor.
• Patients diagnostic reports
• Patients Identity Proof (issued by the government of India)

How does the order be confirmed?

The order will be confirmed only after the receipt of:

• A valid prescription from Doctor
• Import permit if applicable

Is FEXINIDAZOLE available in India?

FEXINIDAZOLE tablet is a (prescription drug, prescription medication, or prescription medicine) pharmaceutical drug that legally requires a medical prescription to be dispensed.

IPN (Indian Pharma Network) helps import cancer medicines on the named patient supply (NPS). Indian Pharma Network is the facilitator providing input

• On availability of Fexinidazole in India (Mumbai, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore, Pune etc.)
• Medicine Price.
• Finding Genuine and reliable sources from the USA, Canada, Europe, and Australia
• Ensuring 100% transparency.

FEXINIDAZOLE can be made available to patients, doctors, and hospitals in Mumbai, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore, Srinagar, Jammu, Jaipur, Chandigarh, Ludhiana, Noida, Gurgaon, Lucknow, and Pune and other cities in India. The order will be confirmed only after the receipt of a valid prescription from the doctor and an import permit.

IPN (Indian Pharma Network) can facilitate the supply of FEXINIDAZOLE (prescription medicines) to all locations in the world and in India after fulfilling the legal requirement (if applicable).

Please contact +91-9310090915 | Toll-Free Number: 1800-889-1064 or write us at info@indianpharmanetwork.in for Fexinidazole price in India. 

We take to guarantee quality and delivery anywhere in the world as per the buyer’s requirements

What is the Generic Name for the trade name drug Fexinidazole®?

Fexinidazole is a Generic Name for the trade name drug Fexinidazolek®.

What is the Manufacturer’s Name of Fexinidazole®?

Fexinidazole® is manufactured by the Drugs for Neglected Diseases Initiative.

Is Fexinidazole® approved by the FDA?

Yes, Fexinidazole® is approved by the FDA. Date of first/initial approval: 16th July 2021.

What is the dosage and form of Fexinidazole® supplied?

Fexinidazole® is supplied as Tablets: 600 mg for oral administration. 

What are the most common side effects of Fexinidazole®? 

The most common side effects of Fexinidazole® are headache, nausea, vomiting, insomnia, asthenia, dizziness, tremor, decreased appetite, upper abdominal pain, hypocalcemia, dyspepsia, back pain, and hyperkalemia.

How much does Fexinidazole cost in India?

The fexinidazole cost in India can vary. In order to procure this HAT medication authentically, you can Call or WhatsApp +91-9310090915 or send mail to info@indianpharmanetwork.in.

What are the storage conditions of Fexinidazole® Tablets?

Store tablets below 30°C (86°F). Store this medication in the original package to protect it from the light and moisture.

Is it safe to buy Fexinidazole® tablets online from India?

Yes, you can buy Fexinidazole tablets online at the best price from the Indian Pharma Network (IPN) if the medicine Fexinidazole has not been approved or is not available in your home country.

What are the Highlights of prescribing information for Fexinidazole®?

Click Here to download full  Fexinidazole prescribing information