Evkeeza (Evinacumab-dgnb)

Evkeeza is an injectable ANGPTL3 (angiopoietin-like 3) inhibitor used together with other low-density lipoprotein-cholesterol (LDL-C) lowering medicines to treat adult and pediatric patients aged 12 years and older, with a type of high cholesterol known as homozygous familial hypercholesterolemia (HoFH).

Recommended Dosage: The recommended dose is 15 mg/kg administered by intravenous (IV) infusion once every 4 weeks (monthly). Do not mix other medicines with Evkeeza injection or administer other medicines at the same time via the same infusion line.

The rate of Evkeeza infusion may be slowed, halted, or discontinued if the respective patient develops any signs of side effects, including hypersensitivity reactions or infusion. 

In case a dose is missed/skipped, administer as promptly as possible. Therefore, this medicine should be scheduled monthly from the date of the final dose.

• Evaluate the low-density lipoprotein-cholesterol (LDL-C) when clinically needed. The low-density lipoprotein-cholesterol lowering effect of Evkeeza (Evinacumab-dgnb) may be measured as early as 14 days after initiation of treatment.
• Evkeeza 15 mg/mL injection is not for use by those with a history of serious hypersensitivity reaction to this medicine or to any of its existing excipients. Serious hypersensitivity reactions, including anaphylaxis, have emerged.
• According to some relevant studies, Evkeeza may be responsible for causing fetal harm if used by a pregnant patient. Those who may become pregnant should use effective contraception during treatment and for at least 5 months after the final dose of Evkeeza.
• It is not specified whether the medicine evinacumab is excreted in human milk. Human IgGs may be excreted in breast milk during the initial few days following birth, which scale down to low concentrations promptly afterward; consequently, a probability of the breastfed child cannot be excluded during this short time span. Afterward, the drug could be used while breastfeeding if clinically required.

Indian Pharma Network is able to source the EVKEEZA (Cancer Treatment Medicines) from across the globe and has the ability to supply. Indian Pharma Network offers its customers worldwide access to the best available treatment.

Indian Pharma Network (IPN) is able to dispense any valid prescription in the shortest possible time. All prescriptions are dispensed and checked by registered pharmacists and dispatched to the Patient’s address only from New Delhi, India.

What is the Generic Name for the trade name drug Evkeeza®?

Evinacumab-dgnb is a Generic Name for the trade name drug Evkeeza®.

What is the Manufacturer’s Name of Evkeeza®?

Evkeeza® is manufactured by Regeneron Pharmaceuticals, Inc. 

Is Evkeeza® approved by the FDA?

Yes, Evkeeza® is approved by the FDA. Date of approval: February 11, 2021.

Is Indian Pharma Network WHO-GDP and ISO 9001 2015 Certified?

Yes, Indian Pharma Network is WHO-GDP and ISO 9001 2015 Certified Pharmaceutical Wholesaler/ Exporter/ Importer, and Evkeeza supplier in India. 

What is the dosage and form of Evkeeza® supplied?

Evkeeza® is supplied as Injection: 345 mg/2.3 mL (150 mg/mL) & 1,200 mg/8 mL (150 mg/mL) solution in single-dose vials for intravenous use. 

What are the most common side effects of Evkeeza®? 

The most common side effects of Evkeeza® are nasopharyngitis, dizziness, influenza-like illness, nausea, and rhinorrhea.

How much does Evkeeza® cost in India?

Evkeeza cost in India is less and can vary. In order to procure this HoFH medicine authentically, one can Call or WhatsApp +91-9310090915 or send mail to info@indianpharmanetwork.in.

What are the storage conditions of Evkeeza®?

Store this medicine in a refrigerator at 2 to 8 °C (36 to 46 °F). Store the vial in the original carton in order to protect it from light. Neither freeze nor shake it. 

Is it safe to buy Evkeeza® online from India?

Yes, you can buy Evkeeza from India at the best price from the Indian Pharma Network (IPN) if the drug Evkeeza has not been approved or is not available in your home country.

What are the Highlights of prescribing information for Evkeeza®?

Click Here to download full  Evkeeza prescribing information.