Epogen (Epoetin Alfa)

Epogen (epoetin alfa) is a type of medicine known as an erythropoiesis-stimulating agent (ESA). It helps the body produce red blood cells (RBCs) and is used to treat certain types of anemia (low red blood cell count).

• Anemia in Chronic Kidney Disease (CKD): It is prescribed for the treatment of patients with CKD, whether they are on dialysis or not.
• Anemia in HIV Patients: Individuals with HIV infection who are taking zidovudine (a type of HIV medicine) may develop anemia. This medicine helps increase their red blood cell (RBC) levels.
• Anemia from Chemotherapy: Some cancer patients receiving myelosuppressive chemotherapy (which affects bone marrow) may experience anemia. This therapeutic drug is used if they have at least two months of chemotherapy planned.
• Before Certain Surgeries: For patients undergoing elective (planned) surgeries that are non-cardiac and non-vascular, this medicinal product helps reduce the need for blood transfusions.

Limitations of Use:
This therapeutic drug does not improve quality of life, reduce fatigue, or enhance overall well-being. It is not recommended in the following cases:

• Cancer patients take only hormonal therapy, biologic drugs, or radiation. It is only for those also on chemotherapy that affects bone marrow.
• Cancer patients receive chemotherapy when the goal is a complete cure.
• Cancer patients whose anemia can be treated with a blood transfusion.
• Surgical patients who are willing to donate their own blood.
• Patients undergoing heart or blood vessel surgeries.
• Patients need an urgent red blood cell transfusion for immediate anemia treatment.

Recommended Dosage: Evaluate iron status before and during Epoetin alfa treatment and maintain iron repletion. Correct or exclude other causes of anemia before starting treatment. Pregnant women, lactating women, neonates, and infants should use only single-dose vials.

• Patients with CKD: The recommended initial dose is 50 to 100 Units/kg 3 times weekly for adults and 50 Units/kg 3 times weekly for pediatric patients. Individualize the maintenance dose of this drug. The intravenous (IV) route is recommended for patients on hemodialysis.
• Patients on Zidovudine due to HIV infection: The recommended dose is 100 Units/kg 3 times weekly.
• Patients with Cancer on Chemotherapy: The recommended dose is 40,000 Units weekly or 150 Units/kg 3 times weekly for adults; and 600 Units/kg intravenously weekly for pediatric patients ≥ 5 years).
• Surgery Patients: The recommended dose is 300 Units/kg per day daily for 15 days or 600 Units/kg weekly.

• Treatment with Epoetin alfa may increase the risk of death, heart attack, stroke, and blood clots. Maintain the lowest hemoglobin levels to avoid these life-threatening complications. Patients with cardiovascular disease should be closely monitored, and treatment should be adjusted based on individual risk factors.
• Cancer patients receiving treatment with this medicinal product may experience accelerated tumor growth or recurrence. Use is restricted to anemia treatment related to chemotherapy. The lowest effective dose should be used, and patients should be informed of the potential risks before starting therapy.
• This medicine can cause or worsen high blood pressure. This may lead to severe cardiovascular events. Blood pressure should be closely monitored, and antihypertensive treatment should be optimized. If hypertension persists despite management, discontinue this treatment to prevent further complications.
• Seizures have been reported in patients with this treatment, particularly during the initial weeks of therapy. Patients with a known history of seizures or rapid hemoglobin increase need careful monitoring. Driving or operating machinery should be avoided if neurological signs develop.
• Some patients may exhibit inadequate or lost response to Epoetin Alfa despite appropriate dosing. Causes may include iron deficiency, infection, chronic inflammation, or bone marrow disorders. Regular monitoring of hemoglobin levels and underlying conditions is essential to ensure treatment effectiveness.
• Epoetin Alfa may trigger an immune-mediated condition called Pure Red Cell Aplasia (PRCA), resulting in severe anemia. Patients developing unexplained anemia or requiring frequent transfusions should discontinue therapy immediately and be evaluated for PRCA with appropriate diagnostic tests.
• Epoetin Alfa can cause life-threatening hypersensitivity reactions, including anaphylaxis and angioedema. Symptoms such as swelling, difficulty breathing, rash, or hypotension require immediate medical attention. Patients with known hypersensitivity to Epoetin Alfa or its components should avoid using this medication.
• Serious skin reactions, including Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), have been reported with Epoetin Alfa. Stop this treatment immediately if widespread rash, blistering, or mucosal involvement occurs.
• Patients should be informed about early signs of serious dermatologic reactions.
• Epoetin Alfa should be used during pregnancy only if the potential benefits outweigh the risks to the fetus. It may pass into breast milk, posing unknown risks to infants. Pregnant or nursing mothers should consult their healthcare provider before using this medication.

What documents are required to import EPOGEN to India?

EPOGEN (epoetin alfa) injections can be imported by patients or government hospitals on the name of the patients only.
The following documentation is required to import the product:

• A valid prescription from a qualified doctor.
• Patients diagnostic reports
• Patient ID proof (issued by the government of India)

How does the order be confirmed?

The order will be confirmed only after the receipt of:

• A valid prescription from the Doctor
• Import permit if applicable

Is EPOGEN available in India?

EPOGEN (epoetin alfa injections) is a (prescription drug, prescription medication, or prescription medicine) pharmaceutical drug that legally requires a medical prescription to be dispensed.

IPN (Indian Pharma Network) helps import cancer medicines on the named patient supply (NPS). Indian Pharma Network is the facilitator providing input

• On availability of Epogen in India (Mumbai, Kolkata,
• Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore, Pune etc.)
• On availability in Gulf countries (Bahrain, Oman, Qatar, Kuwait, Iraq, Saudi Arabia, and the UAE).
• Medicine Price.
• Finding Genuine and reliable sources from the USA, Canada,
• Europe, and Australia
• Ensuring 100% transparency.

EPOGEN can be made available to patients, doctors, and hospitals in Mumbai, Goa, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore, Srinagar, Jammu, Jaipur, Chandigarh, Ludhiana, Noida, Gurgaon, Lucknow, and Pune and other cities in India. The order will be confirmed only after the receipt of a valid prescription from the doctor and an import permit.

IPN (Indian Pharma Network) can facilitate the supply of EPOGEN (prescription medicines) to all locations in the world and India after fulfilling the legal requirement (if applicable).

Please contact +91-9310090915 | Toll-Free Number: 1800-889-1064 or write us at info@indianpharmanetwork.in for Epogen injection prices in India.

We guarantee quality and delivery anywhere in the world as per the buyer’s requirements.

Indian Pharma Network can source EPOGEN (Cancer Treatment Medicines) from across the globe and can supply. Indian Pharma offers its customers worldwide access to the best available treatment.

Indian Pharma Network (IPN) can dispense any valid prescription in the shortest possible time. All prescriptions are dispensed and checked by registered pharmacists and dispatched to the Patient's address only from New Delhi, India.

What is the Generic Name for the trade name drug Epogen®?

Epoetin alfa is a Generic Name for the trade name drug Epogen®.

What is the Manufacturer's Name of Epogen®?

Epogen® is manufactured by Amgen Inc.

Is Epogen approved by the FDA?

Yes, Epogen® is approved by the FDA. Date of first approval: June 1, 1989.

What is the dosage and form of Epogen® supplied?

Epogen is supplied in Injections: 2,000 Units/mL, 3,000 Units/mL, 4,000 Units/mL, and 10,000 Units/mL in single-dose vials, and 20,000 Units/2 mL (10,000 Units/mL) and 20,000 Units/mL in multiple-dose vials containing benzyl alcohol for subcutaneous use.

What are the most common side effects of Epogen® injections?

The most common side effects of Epogen® injections may vary depending on the indications/uses of this medicine. Side effects in:
patients with CKD are: pyrexia, hypertension, muscle spasm, dizziness, arthralgia, medical device malfunction, upper respiratory tract infection, and vascular occlusion.
patients on Zidovudine due to HIV infection are pyrexia, rash, cough, and injection site irritation.
patients with cancer on Chemotherapy are myalgia, nausea, vomiting, arthralgia, headache, bone pain, hypokalemia, stomatitis, cough, weight decrease, leukopenia, hyperglycemia, insomnia, depression, dysphagia, rash, and thrombosis.
patients with surgery are nausea, headache, pruritus, vomiting, injection site pain, cough, chills, deep vein thrombosis, and hypertension.

How much does Epogen® injection cost in India?

Prices of Epogen injections may fluctuate over time because of market dynamics and regulatory changes. For the most transparent and latest Epogen injection cost in India, please Call/WhatsApp +91-9310090915 or send mail to info@indianpharmanetwork.in.

Can Epogen® injections be available in SAARC countries?

Apart from Gulf countries, Epogen® can be available in SAARC countries (India, Afghanistan, Maldives, Nepal, Bangladesh, Bhutan, Pakistan, and Sri Lanka). Indian Pharma Network (IPN) can help facilitate the legal supply of Epogen® injections in these countries. We help ensure legal access to this therapeutic drug through our reliable channels.

Is it safe to buy Epogen® injections online in India?

Yes, one can buy Epogen online in India at the lowest price from the Indian Pharma Network (IPN) if this medicinal product is not (yet) registered or available in their country. We can help facilitate the legal supply of Epogen® injections through legal channels.

What are the storage conditions of Epogen® injections?

Store at 36 to 46°F (2 to 8°C). Do not freeze or shake the medicine. Do not use it if it has been shaken or frozen. Store vials in the original carton until used to protect from light.