Alyftrek (Vanzacaftor, Tezacaftor, and Deutivacaftor)

Alyftrek is a fixed-dose combination medicine of deutivacaftor, tezacaftor, and vanzacaftor used for the treatment of cystic fibrosis (CF) in patients aged six years and older who have at least one F508del mutation or another responsive mutation in the CFTR gene.

Recommended Dosage: Alyftrek can be taken by patients aged 6 years and older but the recommended dosage varies with age and weight. In children aged 6 to less than 12 years who weigh less than 40 kg, three tablets having a total dose of ivacaftor 12 mg together with tezacaftor 60 mg and deutivacaftor 150 mg should be taken. For the age group that weighs 40 kg and more, in this instance aged between 6 to less than 12 years, two tablets comprising ivacaftor 20 mg, tezacaftor 100 mg, and deutivacaftor 250 mg, should be dosed. For patients aged 12 years and older, they are to take the same two tablets every single day.
The recommended dosage should be taken orally (swallow the oral tablets whole) with fat-containing food, once daily, at approximately the same time each day.

• Therapy with Alyftrek may be harmful to the liver and must be exercised with caution so severe pre-existing conditions don’t allow one to take this medication. It is crucial to assess liver damage and pay close attention to tests that monitor the condition of the liver. If liver injury is massive, then stopping the use of this medication is the only option.
• Anaphylaxis is one of the extreme hypersensitivity reactions that is possible for some users. Several symptoms that indicate Heart Woman are rash, swelling, and difficulty in breathing. In case of any allergy, Alyftrek must be stopped immediately while medical care must be sought for an appropriate treatment reaction.
• In particular, children using Alyftrek are at a higher risk of developing cataracts. As an effect, vision gets blurry and becomes accompanied by discomfort in the eyes. Children undergoing long-term treatment for this condition should undergo regular checks on their vision to avoid other problems relating to the eyes.
• Avoid the combination of CYP3A inhibitors because of the significant increase in drug levels to dangerous consequences. Reduce the dose of Alyftrek if necessary while ensuring that the patients will be closely monitored to avoid any severe reactions or overdose as a consequence.
• Alyftrek should only be administered alongside a doctor’s prescription during pregnancy for contraindications indicating that it is risky during this period and pregnancy may also lead to side effects of Alyftrek. In other words, the use of this medication can be dangerous to the fetus, so unless there are sufficient reasons medically to warrant so, the use of this medication should be avoided.
• Deutivacaftor/tezacaftor/vanzacaftor can pass with breast milk and affect the offspring therefore to be on the safer side mothers are advised not to breastfeed till the therapeutic drug is in their bloodstream. If deemed necessary, consult your doctor whether to stop using this medication or breastfeeding or otherwise.

What documents are required to import ALYFTREK to India?

ALYFTREK (vanzacaftor, tezacaftor, and deutivacaftor) tablet can be imported by patients or government hospitals in the name of the patients only.
The following documentation is required to import the product:

• A valid prescription from a qualified doctor.
• Patients diagnostic reports
• Patient ID proof (issued by the government of India)

How does the order be confirmed?

The order will be confirmed only after the receipt of:

• A valid prescription from the Doctor
• Import permit if applicable

Is ALYFTREK available in India?

ALYFTREK (vanzacaftor, tezacaftor, and deutivacaftor tablet) is a (prescription drug, prescription medication, or prescription medicine) pharmaceutical drug that legally requires a medical prescription to be dispensed.

IPN (Indian Pharma Network) helps import cancer medicines on the named patient supply (NPS). Indian Pharma Network is the facilitator providing input

• On availability of Alyftrek in India (Mumbai, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore, Pune etc.)
• On availability in Gulf countries (Bahrain, Oman, Qatar, Kuwait, Iraq, Saudi Arabia, and the UAE).
• Medicine Price.
• Finding Genuine and reliable sources from the USA, Canada, Europe, and Australia
• Ensuring 100% transparency.

ALYFTREK can be made available to patients, doctors, and hospitals in Mumbai, Goa, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore, Srinagar, Jammu, Jaipur, Chandigarh, Ludhiana, Noida, Gurgaon, Lucknow, and Pune and other cities in India. The order will be confirmed only after the receipt of a valid prescription from the doctor and an import permit.

IPN (Indian Pharma Network) can help facilitate the supply of ALYFTREK (prescription medicines) to all locations in the world and India after fulfilling the legal requirement (if applicable).

Please contact +91-9310090915 | Toll-Free Number: 1800-889-1064 or write us at info@indianpharmanetwork.in for Alyftrek Tablets price in India.

We guarantee quality and delivery anywhere in the world as per the buyer’s requirements.

Indian Pharma Network can source ALYFTREK (Cancer Treatment Medicines) from across the globe and can supply. Indian Pharma offers its customers worldwide access to the best available treatment.

Indian Pharma Network (IPN) can dispense any valid prescription in the shortest possible time. All prescriptions are dispensed and checked by registered pharmacists and dispatched to the Patient's address only from New Delhi, India.

What is the Generic Name for the trade name drug Alyftrek®?

Vanzacaftor, tezacaftor, and deutivacaftor is a Generic Name for the trade name drug Alyftrek®.

What is the Manufacturer's Name of Alyftrek®?

Alyftrek® is manufactured by Vertex Pharmaceuticals Inc.

Is Alyftrek® approved by the FDA?

Yes, Alyftrek® is approved by the FDA. Date of first approval: December 20, 2024.

What is the dosage and form of Alyftrek® supplied?

Alyftrek is supplied in fixed-dose combination tablets containing vanzacaftor 4 mg, tezacaftor 20 mg, and deutivacaftor 50 mg; & vanzacaftor 10 mg, tezacaftor 50 mg, and deutivacaftor 125 mg.

What are the most common side effects of Alyftrek® tablets?

The most common side effects of Alyftrek® are cough, nasopharyngitis, upper respiratory tract infection, fatigue, headache, oropharyngeal pain, increased AST, influenza, increased ALT, rash, and sinus congestion.

How much does the Alyftrek® tablet cost in India?

Prices of Alyftrek tablets may fluctuate over time because of market dynamics and regulatory changes. To get the most recent details on Alyftrek tablet cost in India, please Call/WhatsApp +91-9310090915 or send mail to info@indianpharmanetwork.in.

Can Alyftrek® tablets be available in SAARC countries?

Apart from Gulf countries, Alyftrek® can be available in SAARC countries (India, Afghanistan, Maldives, Nepal, Bangladesh, Bhutan, Pakistan, and Sri Lanka). Indian Pharma Network (IPN) can help facilitate the legal supply of Alyftrek® tablets in these countries. We help ensure legal access to this therapeutic drug through our reliable channels.

Is it safe to buy Alyftrek® tablets online in India?

Yes, one can buy Alyftrek tablets online in India at the lowest price from the Indian Pharma Network (IPN) if this medicinal product is not (yet) registered or available in their country. We can facilitate the legal supply of Alyftrek® tablets through legal channels.

What are the storage conditions of Alyftrek® tablets?

Store the oral tablets of Alyftrek® at 20 to 25°C (68 to 77°F); excursions permitted to 15 to 30°C (59 to 86°F).