What is Kineret?
Kineret, also known by its generic name anakinra, is a biologic medicinal product. It is supplied as 100 mg/0.67mL prefilled syringes. Commercially Kineret 100 mg can be accessed in a pack of 28 injections. This therapeutic drug is used for treating several inflammatory conditions, including Rheumatoid Arthritis (RA), Neonatal-Onset Multisystem Inflammatory Disease (NOMID), and Deficiency of Interleukin-1 Receptor Antagonist (DIRA). This medicine works by blocking the activity of interleukin-1 (IL-1), a protein involved in the inflammatory response. By inhibiting IL-1, it helps reduce inflammation and its associated symptoms.
Rheumatoid Arthritis (RA)
Overview: Rheumatoid Arthritis (RA) is a chronic autoimmune disorder characterized by persistent inflammation of the joints, leading to pain, swelling, stiffness, and eventually joint damage. It can significantly impair daily functioning and quality of life.
Kineret for RA: It is used to manage RA in patients who have not responded adequately to other disease-modifying antirheumatic drugs (DMARDs). It is administered via subcutaneous (SC) injection, typically once daily.
Benefits:
- Reduction of Symptoms: Kineret effectively reduces joint pain, swelling, and stiffness, improving overall joint function.
- Prevention of Joint Damage: By controlling inflammation, Kineret helps prevent long-term joint damage and deformity.
- Improved Quality of Life: Patients often experience a significant improvement in their ability to perform daily activities.
Side Effects: Common side effects include injection site reactions, headaches, and increased risk of infections. Serious side effects, though rare, can include severe infections, low white blood cell counts, and allergic reactions.
Neonatal-Onset Multisystem Inflammatory Disease (NOMID)
Overview: NOMID, also known as Chronic Infantile Neurological Cutaneous and Articular (CINCA) syndrome, is a rare, inherited autoinflammatory disorder. It presents in infancy with symptoms like fever, rash, joint inflammation, and central nervous system involvement, including chronic aseptic meningitis.
Kineret for NOMID: Kineret is the first FDA-approved treatment for NOMID, offering significant relief from its debilitating symptoms. It is administered daily via subcutaneous (SC) injection.
Benefits:
- Control of Inflammation: Kineret significantly reduces systemic inflammation, alleviating symptoms like fever and rash.
- Neurological Improvement: It helps manage neurological symptoms, reducing headaches and other CNS complications.
- Enhanced Quality of Life: Patients often see substantial improvements in their overall health and daily functioning.
Side Effects: Side effects are similar to those seen in RA treatment, including injection site reactions and an increased risk of infections. Continuous monitoring is essential to manage potential adverse effects effectively.
Deficiency of Interleukin-1 Receptor Antagonist (DIRA)
Overview: DIRA is an ultra-rare genetic disorder where a deficiency in the interleukin-1 receptor antagonist leads to unchecked inflammation. This condition presents with symptoms such as severe skin and bone inflammation, fever, and systemic inflammation from birth.
Kineret for DIRA: This medicinal product is a lifesaving treatment for DIRA, providing a crucial means to control inflammation. Daily subcutaneous injections are required.
Benefits:
- Life-Saving Intervention: For many patients with DIRA, Kineret is essential to survival, effectively controlling severe inflammatory symptoms.
- Improved Health Outcomes: It reduces skin and bone inflammation, preventing complications and improving overall health.
- Enhanced Development: By controlling systemic inflammation, Kineret supports normal growth and development in affected infants and children.
Side Effects: The side effects are consistent with those observed in other conditions treated with Kineret, including injection site reactions and an increased risk of infections. Due to the severe nature of DIRA, the benefits often far outweigh the risks.
Conclusion:
Kineret is a versatile and promising medicine that has transformed the treatment landscape for several severe inflammatory conditions, including RA, NOMID, and DIRA. By targeting the interleukin-1 pathway, it helps manage symptoms, prevent disease progression, and improve the quality of life (QoL) for many patients. As with any therapeutic drug, monitoring and managing side effects is crucial to ensure the best outcomes for patients. With its proven efficacy and safety profile, Kineret continues to be a vital tool in the fight against inflammatory diseases.
Is Kineret Approved in India?
No, Kineret in India is yet to be approved. However, patients in India can buy Kineret online at the most reasonable price through the Indian Pharma Network (IPN). We facilitate legal access to hard-to-access medicines not available locally.
How can I inquire about purchasing Kineret from IPN?
Patients from India, Afghanistan, Bangladesh, Bhutan, Maldives, Nepal, Pakistan, and Sri Lanka can send their inquiries via mail: info@indianpharmanetwork.in or contact IPN through Call/WhatsApp: +91 9310090915. The IPN team is available to assist with any questions and provide complete guidance on the purchasing process.
What is the Price of Kineret in India?
The price of Kineret in India can vary depending on the supplier and the dosage required. To get the most accurate and up-to-date information on the Kineret 100 mg price, it is best to contact the IPN directly or visit our website.
Is it safe to buy Kineret online from the IPN?
Yes, it is safe. Indian Pharma Network (IPN) is a reputable provider of pharmaceuticals, including Kineret, ensuring high-quality standards and reliable service.
How can I get Kineret if it’s not available in my country?
If Kineret is unavailable in your country, you can contact the Indian Pharma Network (IPN). IPN specializes in sourcing and supplying medications that may not be readily available in certain regions, ensuring patients can access necessary treatments. Patients from the United States, Germany, France, United Kingdom, Italy, Spain, Canada, Japan, Australia, Bangladesh, Sri Lanka, UAE, and the Netherlands can send their inquiries to buy Kineret injections online at the best price.
Does the IPN offer support in obtaining Kineret?
Yes, the Indian Pharma Network (IPN) offers comprehensive support in obtaining Kineret. We can assist with sourcing the therapeutic drug, managing the importation logistics, and ensuring compliance with regulatory requirements.
Can international patients buy Kineret from IPN?
Yes, patients from a wide range of countries can buy Kineret 100 mg/0.67ml from IPN. These countries include Belgium, Canada, China, Costa Rica, Dominican Republic, Ethiopia, Fiji, France, French Polynesia, Germany, Guatemala, Iraq, Italy, Japan, Jordan, Kenya, Lebanon, Morocco, Netherlands, New Caledonia, New Zealand, Oman, Papua New Guinea, Peru, Qatar, Russia, Spain, Switzerland, Tanzania, Tunisia, the UK, and the USA.
References:
https://www.kineretrx.com/
https://rarediseases.org/rare-diseases/neonatal-onset-multisystem-inflammatory-disease/
