Inrebic (Fedratinib)
- Medicine Name: Inrebic
- Generic Name: Fedratinib
- Dosage Form & Strength: Capsules: 100 mg
- Manufactured By: Celgene Corporation
Inrebic is a kinase inhibitor used to treat adult patients with intermediate-2 or high-risk primary or secondary (post-polycythemia vera or post-essential thrombocythemia) myelofibrosis (MF).
Recommended Dosage: The recommended dosage is 400 mg taken by mouth once daily for patients with a baseline platelet count beyond or equal to 50 x 109/L. The inrebic capsules may be taken with or without food. Use with a high fat meal may reduce the incidence of vomiting and nausea.
Modify the dose of inrebic for patients using concomitant strong CYP3A4 inhibitors, and in patients with severe renal impairment (creatinine clearance (CLcr) 15 mL/min to 29 mL/min). If a dose is missed, the next scheduled dose needs to be taken the following day.
- Severe and fatal encephalopathy, including Wernicke’s encephalopathy, may occur. Assess thiamine levels in all patients before starting inrebic 100 mg capsule, periodically during treatment. Do not start treatment in patients with thiamine deficiency; replete thiamine prior to initiation of treatment.
- Therapy with Fedratinib can cause anemia and thrombocytopenia. Obtain a complete blood count (CBC) at baseline, periodically during treatment. For Grade-3 thrombocytopenia with active bleeding or Grade-4 thrombocytopenia, interrupt therapy until resolved to ≤ Grade-2. Restart dose at 100 mg in a day below the last given dose and platelets should be monitored.
- Gastrointestinal toxicities are the common side effects in Fedratinib-treated patients. Consider providing apt prophylactic antiemetic therapy (e.g., 5-HT3 receptor antagonists) during therapy with fedratinib 100 mg capsule. Monitor thiamine levels and replete as required.
- Monitor hepatic function, periodically during therapy. For Grade-3 or higher ALT/AST elevations (higher than 5 × ULN), interrupt Fedratinib dose until resolved to Grade-1 or less or to baseline. Restart dose at 100mg daily below the last given dose. If re-occurrence of a Grade-3 or higher elevation of ALT/AST, interrupt treatment with Fedratinib.
- Monitor amylase and lipase, periodically during treatment. For Grade-3 or higher amylase or lipase elevations, interrupt Fedratinib until resolved to Grade-1 or less or to baseline. Restart dose at 100mg in a day below the final given dose.
What documents are required to import INREBIC to India?
INREBIC (fedratinib) capsules can be imported by patients or government hospitals on the name of the patients only.
The following documentation required to import the product:
- Valid prescription from a qualified doctor.
- Patients diagnostic reports
- Patients Identity Proof (issued by government of India)
How does order be confirmed?
The order will be confirmed only after the receipt of:
- Valid prescription of Doctor
- Import permit if applicable
Is INREBIC available in India?
INREBIC (fedratinib capsules) is a (prescription drug, prescription medication or prescription medicine) pharmaceutical drug that legally requires a medical prescription to be dispensed.
IPN (Indian Pharma Network) helps import cancer medicines on the named patient supply (NPS). Indian Pharma Network is facilitator providing input
- On availability of Inrebic in India (Mumbai, Pune, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, and Bangalore)
- Medicine Price.
- Finding Genuine and reliable source from Canada, Europe, USA and Australia
- Ensuring 100% transparency.
INREBIC can be made available to patients, doctors and hospitals at Mumbai, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore, Srinagar, Jammu, Jaipur, Chandigarh, Ludhiana, Noida, Gurgaon, Lucknow and Pune and other cities in India. The order will be confirmed only after the receipt of a valid prescription from the doctor and import permit.
IPN (Indian Pharma Network) can facilitate the supply of INREBIC (prescription medicines) to all locations in the world and in India after fulfilling the legal requirement (if applicable)
Please contact +91-9310090915 | Toll-Free No: 1800-889-1064 or write us at info@indianpharmanetwork.in for Inrebic 100 mg Capsule price in India.
We take guarantee of quality and delivery anywhere in the world as per the buyer’s requirements.
Indian Pharma Network is able to source the INREBIC (Cancer Treatment Medicines) from across the globe, and has the ability to supply. Indian Pharma offers its customers worldwide access to the best available treatment.
Indian Pharma Network is able to dispense any valid prescription in the shortest possible time. All prescriptions are dispensed and checked by registered pharmacists and dispatched to the Patient’s address only from New Delhi, India.
What is the Generic Name for the trade name drug Inrebic®?
Fedratinib is Generic Name for the trade name drug Inrebic®.
What is the Manufacturer Name of Inrebic®?
Inrebic® is manufactured by Celgene Corporation.
Is Inrebic® approved by the FDA?
Yes, Inrebic® is first approved by the FDA. Date of approval: August 16, 2019.
What is the dosage and form of Inrebic® supplied?
Inrebic® is supplied as Capsules: 100 mg for oral administration.
Is Inrebic® a chemo medicine?
Inrebic® is an anti-cancer (antineoplastic) targeted agent. It is classified as a JAK2 inhibitor.
What are the most common side effects due to Inrebic®?
Most common side effects due to Inrebic® may include: nausea, diarrhea, anemia, and vomiting.
How much does Inrebic® cost in India?
The cost of Inrebic 100 mg Capsule in India is reasonable. In order to procure this myelofibrosis (MF) medicine authentically, you can call or WhatsApp +91-9310090915 or send mail to info@indianpharmanetwork.in.
What are the storage conditions of Inrebic®?
Store Inrebic below 86°F (30°C). Store the medication in a closed container at room temperature, away from direct light, moisture, and heat. Keep from freezing.
Is it safe to buy Inrebic® online in India?
Yes, You can buy Inrebic 100 mg Capsule online in India legitimately from https://www.indianpharmanetwork.in/ if Inrebic has not been approved or is not available in your country.
Is Indian Pharma Network certified by WHO-GDP and ISO 9001:2008 authorities?
Yes, We have certification from the top-most authorities like WHO-GDP and ISO 9001:2008. We’re a leading and authentic Inrebic supplier and Inrebic wholesaler in India. We can help you to access this myelofibrosis (MF) drug at the lowest affordable price.
What are the Highlights of prescribing information for Inrebic®?
Click Here to download full inrebic prescribing information.
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